Health characteristics and predicted 10-year risk for a first atherosclerotic cardiovascular disease (ASCVD) event using the Pooled Cohort Risk Equations among US adults who are free of cardiovascular disease

Physiology & Behavior
Paul D Loprinzi, Allison Nooe

Abstract

No study has used the recently developed Pooled Cohort Equations to examine the associations of various health behaviors and health characteristics on 10-year risk of a first atherosclerotic cardiovascular disease (ASCVD) event. Data from the 2003-2006 National Health and Nutrition Examination Survey were used. 10-year risk of a first ASCVD event was assessed from the Pooled Cohort Equations. Physical activity was assessed via accelerometry; weight status was assessed via measured body mass index; smoking was assessed via cotinine levels; and dietary behavior was calculated from the healthy eating index. After adjustments, and compared to those with 0 positive health characteristics, those with 1, 2, 3, and 4 health characteristics, respectively, had a 87% (OR=0.13, p<0.001), 95% (OR=0.05, p<0.001), 95% (OR=0.05, p<0.001), and 96% (OR=0.04, p=0.001) reduced odds of being at an elevated risk for a first ASCVD event in the next 10 years. A dose-response association was observed between number of positive health characteristics and the 10-year risk of a first ASCVD event.

References

Nov 19, 2005·Medicine and Science in Sports and Exercise·Kong Y Chen, David R Bassett
Sep 27, 2006·Journal of the American Dietetic Association·Janet A ToozeVictor Kipnis
May 23, 2008·Medicine and Science in Sports and Exercise·Charles E Matthews
Sep 18, 2008·BMJ : British Medical Journal·Rob M van DamFrank B Hu
May 9, 2012·Preventive Medicine·Earl S FordSimon Capewell
Jun 5, 2013·American Journal of Epidemiology·Haitham M AhmedRoger S Blumenthal
Apr 1, 2014·JAMA : the Journal of the American Medical Association·Paul MuntnerMonika M Safford
Oct 30, 2014·Stroke; a Journal of Cerebral Circulation·Jong-Ho ParkHyejin Lee

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