Abstract
The components of the cardiometabolic syndrome (CMS) increase the risk of coronary artery disease (CAD). The authors compared 12-month costs of subjects with different number of components of the CMS. In claims data from a large health benefits company, 383,420 individuals with the first International Classification of Diseases, Ninth Revision codes for hypertension, diabetes, lipid abnormalities, and obesity were identified. Patients were stratified according to presence of CAD and the number of components of the CMS. Twelve-month costs were added after the identification of the risk factor. Mean annual costs increased with the number of components of CMS both in those with and without CAD, even after adjusting for age, sex, and comorbidities (P<.01). Similar trends were seen for medical and pharmacy costs. The adjusted total annual health care cost in those with an isolated component of the CMS was $5564 (95% confidence interval: $5491-$5631) while in those with 4 components was $12,287 (95% confidence interval: $11,987-$12,587). Individuals with accumulating components of the CMS have higher health care costs regardless of age, sex, and other comorbidities.
References
Jun 1, 1992·Journal of Clinical Epidemiology·R A DeyoM A Ciol
May 15, 1998·Journal of the American College of Cardiology·S G EllisE J Topol
Sep 4, 1998·Journal of Health Services Research & Policy·A Briggs, A Gray
Jul 27, 2001·Medical Care·E L EisensteinD B Mark
May 30, 2002·The American Journal of Medicine·Richard W GrantJames B Meigs
Nov 7, 2002·Archives of Internal Medicine·Jennifer L WolffGerard Anderson
Jun 17, 2004·JAMA : the Journal of the American Medical Association·Allison A HedleyKatherine M Flegal
Mar 2, 2005·Annals of Internal Medicine·William H HermanUNKNOWN Diabetes Prevention Program Research Group
Apr 20, 2005·Medical Care·Elena Birman-DeychBrian F Gage
May 11, 2005·Archives of Internal Medicine·Martha L DaviglusJeremiah Stamler
Jun 29, 2005·Diabetes Care·Earl S Ford
Nov 9, 2005·Circulation·Peter W F WilsonJames B Meigs
Apr 26, 2006·The American Journal of Cardiology·Claudia R PischkeDean Ornish
May 20, 2009·Metabolic Syndrome and Related Disorders·Edmond P WickhamJoseph H Laver
Citations
Dec 21, 2010·Metabolic Syndrome and Related Disorders·Gregory A Nichols, Edward J Moler
Nov 12, 2014·The Journal of Physiology·Jefferson C FrisbeePaul D Chantler
Sep 27, 2013·Mediators of Inflammation·Roozbeh KhosraviSimon D Tran