Abstract
A medical surveillance program has been established for 482 persons who were potentially exposed to polychlorinated biphenyls (PCBs), dibenzo-p-dioxins, and dibenzofurans from an electrical transformer fire in a Binghamton, NY office building in 1981. Vital Record and Cancer Registry data, medical records, and mail questionnaires were used to assess mortality, symptomatology, cancer incidence, and reproductive events through 1984. The numbers of deaths, cancers, fetal deaths, and infants with low birth weight or congenital malformations were similar to those expected on the basis of age- and sex-specific rates for upstate New York and other comparison populations. Two suicides were observed compared with 0.31 expected, but the difference was not statistically significant. After adjustment for possible confounders, persons with the greatest degree of potential exposure were significantly more likely than those with less exposure to report unexplained weight loss (relative risk [RR] = 12.80), muscle pain (RR = 5.07), frequent coughing (RR = 4.14), skin color changes (RR = 3.49), and nervousness or sleep problems (RR = 3.19). The possibility of recall bias and the intervening effects of stress, however, weaken the conclusion that ...Continue Reading
References
May 31, 1979·Annals of the New York Academy of Sciences·J R AllenJ P Van Miller
May 31, 1979·Annals of the New York Academy of Sciences·F PocchiariA Zampieri
Jan 1, 1979·Journal of Chronic Diseases·D L Sackett
Oct 17, 1987·Lancet·G J MacfarlaneC Scully
Feb 13, 1987·JAMA : the Journal of the American Medical Association
Oct 1, 1986·Environmental Research·A D StarkH L Vallet
Jan 1, 1986·Journal of Toxicology. Clinical Toxicology·J OsterlohC Becker
Nov 1, 1986·Archives of Environmental Health·E F FitzgeraldD T Janerich
Jun 1, 1986·Journal of Occupational Medicine. : Official Publication of the Industrial Medical Association·R R Monson
Apr 1, 1985·Scandinavian Journal of Work, Environment & Health·A M SeppäläinenO Elo
Jun 1, 1985·British Journal of Industrial Medicine·A FischbeinM S Wolff
Mar 1, 1985·American Journal of Public Health·C E LawrenceA J Kuntz
Apr 1, 1983·British Journal of Obstetrics and Gynaecology·S L Barron
Jan 1, 1981·Epidemiologic Reviews·J N LogueH Hansen
Jan 1, 1981·Archives of Environmental Health·J Pazderova-VejlupkováL Jirásek
Citations
Oct 19, 1991·Lancet·A ManzH Waltsgott
Nov 1, 1996·Archives of Environmental Health·S F HsiehY C Ko
Jan 1, 1994·Critical Reviews in Toxicology·S H Safe
May 1, 1996·Critical Reviews in Toxicology·S TasD Lison
Jul 27, 2015·Journal of the American Academy of Dermatology·Andrew T PattersonDirk M Elston
Jan 1, 1995·International Archives of Occupational and Environmental Health·S A HwangA Stark