Health ranking of ingested semi-volatile organic compounds in house dust: an application to France

Indoor Air
Nathalie BonvallotPhilippe Glorennec

Abstract

People spend most of their time indoors. Dust settled in the home may be contaminated by semi-volatile organic compounds (SVOCs). Exposure to these compounds is of great concern, in particular for infants. Their number is large so arose the question of which ones should be selected for dust ingestion exposure assessment. This work proposes a health ranking of SVOCs ingested through settled dust. This ranking is based on the toxicity and contamination of SVOCs in dust. Data on compounds and contamination was retrieved from a bibliographic review. Where possible, toxicity data was retrieved from databases, otherwise it was calculated from raw data. One hundred and fifty-six SVOCs were selected, 66 of which were prioritized. Forty-two could not be prioritized because contamination data was below the limit of detection, and 48 could not be prioritized because there was no contamination or toxicity data. The top-ranked compounds were phthalates, pesticides, short-chain chlorinated paraffins, PBDEs, PFCs, organotins, PCBs, and PAHs. As most of these have reprotoxic and neurotoxic properties, an integrated multi-pollutants approach to exposure is required and simultaneous measurement methods should be developed. The large number of co...Continue Reading

References

Dec 1, 1992·Regulatory Toxicology and Pharmacology : RTP·I C Nisbet, P K LaGoy
Jun 1, 1990·Japanese Journal of Cancer Research : Gann·A NyskaB Klein
Apr 1, 1972·Atmospheric Environment·I Andersen
Oct 1, 1995·Regulatory Toxicology and Pharmacology : RTP·H R Pohl, H G Abadin
Jun 10, 1998·Regulatory Toxicology and Pharmacology : RTP·C Winder, D Gonzalez-Calderon
Nov 11, 1999·Toxicology Letters·D E StevensonJ E Klaunig
Jul 12, 2002·Archives of Toxicology·Shinshi Oishi
Oct 4, 2002·Environmental Health Perspectives·Paul J LioyJames R Millette
Nov 7, 2002·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·S Oishi
May 15, 2004·The Science of the Total Environment·H FrommeH Rüden
Oct 9, 2004·Environmental Health Perspectives·Carl-Gustaf BornehagLinda Hägerhed-Engman
Mar 3, 2005·The Science of the Total Environment·M WensingT Salthammer
May 18, 2005·Regulatory Toxicology and Pharmacology : RTP·Qiyu ZhaoMichael Dourson
Jun 24, 2005·International Journal of Hygiene and Environmental Health·Gabriele LengHelga Idel
Oct 28, 2005·Journal of Environmental Monitoring : JEM·Cariton KubwaboLeonora Marro
Jul 11, 2006·Toxicological Sciences : an Official Journal of the Society of Toxicology·Martin Van den BergRichard E Peterson
Jul 13, 2006·Risk Analysis : an Official Publication of the Society for Risk Analysis·Matthias WormuthKonrad Hungerbühler
Apr 3, 2007·Environmental Science & Technology·Nerissa WuThomas F Webster
May 22, 2007·Risk Analysis : an Official Publication of the Society for Risk Analysis·Jianping XueStuart Shalat
Dec 14, 2007·Environmental Science & Technology·Jiping ZhuMahiba Shoeib
Jan 5, 2008·Environmental Health Perspectives·Andreas Kortenkamp
Jan 17, 2008·Environmental Health Perspectives·Barbara KolarikJan Sundell
Feb 6, 2008·International Journal of Andrology·Andreas Kortenkamp
Feb 21, 2008·Environmental Science & Technology·Abou-Elwafa Abdallah MohamedAdrian Covaci

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Citations

Jun 15, 2011·Environmental Science & Technology·Fabien MercierBarbara Le Bot
Mar 5, 2014·Environmental Science & Technology·Olivier BlanchardBarbara Le Bot
Oct 25, 2014·Environmental Science. Processes & Impacts·A L HinwoodJ Ø Odland
Mar 10, 2016·Neurotoxicology·Cécile ChevrierSylvaine Cordier
Feb 13, 2016·Current Opinion in Pediatrics·Gary L Ginsberg, Sophie J Balk
Jul 5, 2016·International Journal of Environmental Research and Public Health·Gary GinsbergBrenda Foos
Jan 16, 2021·Environmental Science & Technology·Tianren WuBrandon E Boor
Apr 26, 2020·Environmental Research·M Velázquez-Gómez, S Lacorte

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