Health-Related Quality of Life After Spine Surgery for Primary Bone Tumour

Current Treatment Options in Oncology
Raphaële Charest-MorinCharles G Fisher

Abstract

Treatment of primary bone tumours (PBT) of the spine is complex, often involving numerous surgical and oncology disciplines. Surgical en bloc resection with oncologically appropriate margins is the modality of choice when treating malignant PBT. En bloc resection with wide or marginal margins appears to offer better local and systemic control of the disease. This type of surgical resection can also be considered when treating benign aggressive tumours such as aneurysmal bone cyst, giant cell tumour and osteoblastoma. Although these surgeries respect oncologic principles, significant morbidity and mortality are associated. Adverse event collection is highly variable in the literature and mostly from retrospective studies. Wound complication, neurologic deficit and significant blood loss are encountered with surgical resection of PBT of the mobile spine and especially, the sacrum. The adverse event profile of these surgeries is high even in experienced quaternary referral centres. Therefore, primary spinal tumour resection is best performed in experienced centre with adequate multidisciplinary support. Furthermore, prospective and systematic adverse event data collection should be developed to ensure accurate data. The impact of ...Continue Reading

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Citations

Aug 18, 2017·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Stefano BorianiAlessandro Gasbarrini
Dec 1, 2018·Journal of Neurosurgery. Spine·Nicolas DeaUNKNOWN AOSpine Knowledge Forum Tumor
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Dec 19, 2019·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·A S E McCarthyD Steffens
Jun 23, 2016·Cardiovascular and Interventional Radiology·Georgia TsoumakidouAfshin Gangi
Mar 30, 2017·Neurosurgery·Nicolas DeaCharles Fisher

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