Jun 28, 2013

Health-related quality of life and congenital heart disease in Australia

Journal of Paediatrics and Child Health
Karen J EaglesonFrances M Boyle


To determine whether, in children with congenital heart disease (CHD), disease severity is associated with health-related quality of life (HRQOL) and impact on the family. Cross-sectional, single-centre study comparing HRQOL outcomes of age and sex matched children with hypoplasia of the left ventricle (HLV) (n = 31) and tetralogy of Fallot (n = 29) was performed in Queensland, Australia. HRQOL was assessed using generic and disease-specific components of the Paediatric Quality of Life Inventory Measurement Model (PedsQL). Intra-diagnostic age group comparisons of HRQOL were examined. Impact of CHD on families and parental HRQOL was assessed using the PedsQL Family Impact Scale. Child and parent-proxy reporting indicate children with HLV have significantly lower overall HRQOL than children with tetralogy of Fallot across generic domains of HRQOL (P < 0.0001), with significantly lower scores in physical (P < 0.0001) and psychosocial (P < 0.0001) health domains. No significant difference in child reporting across domains of the Cardiac Module is evident. Parent-proxy reporting indicates significantly lower scores on the symptom scales for children with HLV (P < 0.001), with greater cognitive problems (P < 0.02) and perceived trea...Continue Reading

  • References37
  • Citations21


  • References37
  • Citations21

Mentioned in this Paper

Health Status
Left Ventricular Structure
Pediatric Quality of Life Inventory
Congenital Heart Disease
Pediatric Discipline
Congenital Heart Defects
Heart Diseases
Tetralogy of Fallot
Postoperative Complications

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