PMID: 16509524Mar 3, 2006Paper

Health related quality of life and psychological outcome in patients treated for craniopharyngioma in childhood

Journal of Pediatric Endocrinology & Metabolism : JPEM
C C PedreiraM R Zacharin

Abstract

Patients with craniopharyngioma are at risk for many adverse effects related to the tumour's invasive behaviour and its proximity to many vital structures. Profound psychosocial problems, memory impairment, pituitary and hypothalamic dysfunction in addition to the physical handicap of visual loss are frequently recognized sequelae of craniopharyngioma treatment. To examine health related quality of life (QoL) and psychological outcomes of patients treated for craniopharyngioma at the Royal Children's Hospital, Melbourne, between January 1980 and September 2003. Seven (17.4%) of 46 (26 male) had died. Thirty-nine remained, of whom 30 were contactable. Eighteen of 30 (8 male), mean age 21.2 +/- 6.7 years, agreed to evaluation, of whom 16/18 (88.9%) had three or more pituitary hormone deficiencies, 11/18 had visual impairment and 9/18 obesity. The Adult GH-Deficient Assessment (AGHDA) and Psychological General Well-Being (PGWB) questionnaires were employed to assess quality of life in patients and age- and sex-matched healthy controls. Additional psychological assessment, including intellectual and academic skills, emotional function, and adaptive behaviour, had been undertaken in 12 patients at a previous time. High levels of phy...Continue Reading

References

Jan 1, 1992·Journal of Neurosurgery·H J HoffmanS I Blaser
Aug 1, 1990·The Journal of Neuroscience Nursing : Journal of the American Association of Neuroscience Nurses·T Shiminski-Maher, M Rosenberg

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Citations

Sep 11, 2012·Pituitary·Eva Marie ErfurthSigridur Bara Fjalldal
Oct 29, 2009·Optometry : Journal of the American Optometric Association·Cynthia Overly
Feb 5, 2009·Pediatric Blood & Cancer·Eugenia P DolsonThomas E Merchant
Oct 22, 2008·Pediatric Blood & Cancer·Arthur K LiuNicholas K Foreman
Apr 14, 2018·Pediatric Hematology and Oncology·Alice Ann HollandPeter L Stavinoha
Jun 23, 2018·Pediatric Blood & Cancer·Rachel K PetersonHeather M Conklin
Jan 7, 2011·The Journal of Neuroscience Nursing : Journal of the American Association of Neuroscience Nurses·Deborah B CromE Brannon Morris
Jun 8, 2015·Current Opinion in Oncology·Fiona Schulte
Oct 8, 2019·The Journal of Clinical Endocrinology and Metabolism·Klaus Christian MendeUNKNOWN “pituitary working group” of the German Society of Endocrinology (DGE)
May 12, 2016·Journal of Pediatric Endocrinology & Metabolism : JPEM·Naomi CookJohn Hart
Dec 17, 2014·Journal of Pediatric Endocrinology & Metabolism : JPEM·Eva Marie Erfurth
Mar 3, 2006·Journal of Pediatric Endocrinology & Metabolism : JPEM·Meropi Toumba, Richard Stanhope
Sep 16, 2015·Journal of Neuro-oncology·Jale ÖzyurtChristiane M Thiel
Aug 8, 2020·Pediatric Blood & Cancer·Christina M SharkeyLarry L Mullins

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