Health-related quality of life impact of a transcatheter pacing system

Journal of Cardiovascular Electrophysiology
Fleur V Y TjongMicra Investigators

Abstract

Transcatheter pacing systems (TPS) provide a novel, minimally invasive approach in which a miniaturized, leadless pacemaker (PM) is transfemorally implanted in the right ventricle. We evaluated the health-related quality of life (HRQoL) impact, patient satisfaction, and activity restrictions following TPS in a large prospective multicenter clinical trial. Patients who underwent a Micra TPS implantation between December 2013 and May 2015 were included. HRQoL impact was evaluated using the Short-Form-36 (SF-36) questionnaire at baseline, 3, and 12 months. Patient satisfaction was assessed using a three-item questionnaire determining recovery, activity level, and esthetic appearance at 3 months. Implanting physicians compared the patient activity restrictions for TPS to traditional PM therapy. A total of 720 patients were implanted with a TPS (76 ± 11 years; 59% male). Of these patients, 702 (98%), 681 (95%), and 635 (88%) completed the SF-36 at baseline, 3 and 12 months, respectively. Improvements were observed at 3 and 12 months in all SF-36 domains and all attained statistical significance. Of 693 patients who completed the patient satisfaction questionnaire, 96%, 91%, 74% were (very) satisfied with their esthetic appearance, r...Continue Reading

Associated Clinical Trials

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Citations

Nov 1, 2018·Journal of Cardiovascular Electrophysiology·Michael Rehorn, Albert Y Sun
Apr 11, 2019·Herzschrittmachertherapie & Elektrophysiologie·Salma HajKhederChristian Butter
May 26, 2018·PLoS Computational Biology·Caroline H RoneyEdward J Vigmond
Oct 29, 2019·Expert Review of Medical Devices·Niek E G BeurskensReinoud E Knops
Dec 17, 2019·Journal of Cardiovascular Electrophysiology·Pilar Cabanas-GrandíoAndrés Íñiguez Romo
Oct 23, 2020·Pacing and Clinical Electrophysiology : PACE·Antonio CurnisLuca Bontempi
Feb 10, 2021·Current Problems in Cardiology·Michael Lawren CoIndranill Basu-Ray
Jun 26, 2021·Journal of the American Heart Association·Linh NgoIsuru Ranasinghe
Aug 30, 2021·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Michael GliksonKlaus K Witte
Aug 30, 2021·European Heart Journal·Michael GliksonUNKNOWN ESC Scientific Document Group

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