Health-related quality of life in Italian patients with narcolepsy: the SF-36 health survey

Sleep Medicine
Luca VignatelliGINSEN (Gruppo Italiano Narcolessia-Studio Epidemiologico Nazionale)

Abstract

To evaluate the psychometric performances of the 36-item short form (SF-36), a tool measuring health-related quality of life (HRQoL) in patients with narcolepsy or other sleep disorders, presenting excessive daytime sleepiness (EDS) as the main symptom. To compare the HRQoL of patients with narcolepsy with the Italian norm. To disclose the clinical predictors influencing the HRQoL. One hundred and eight adults with narcolepsy, 115 with obstructive sleep apnea syndrome (OSAS) and 42 with idiopathic hypersomnia (IH) enrolled for a multicentric cross-section study employing self-administered questionnaires investigating the HRQoL (SF-36), EDS and cataplexy. A psychometric analysis and the standardized scoring of the 8 scales of the SF-36 were performed. The correlation between SF-36 scales and clinical features of narcolepsy was measured by a multiple linear regression analysis. SF-36 satisfied the recommended psychometric standards. Patients with narcolepsy had all domains except Bodily Pain lower than the Italian norm. Some of the variance of Physical Functioning (R(2) 0.07), Role functioning-Physical (R(2) 0.31), General Health (R(2) 0.15), Vitality (R(2) 0.10), Social Functioning (R(2) 0.21) and Role functioning-Emotional (R(2...Continue Reading

References

Jan 1, 1988·Psychopharmacology·W A CorrigallK M Coen
Apr 4, 2001·Journal of Sleep Research·E DanielsJ M Shneerson
Oct 31, 2001·Neuroepidemiology·R RinaldiE Lugaresi
Aug 18, 2004·Sleep Medicine Reviews·M Johns

❮ Previous
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Citations

Mar 2, 2013·Sleep·Regis LopezYves Dauvilliers
Mar 22, 2013·BMC Medicine·Yves DauvilliersSophie Bayard
Jan 1, 2005·International Journal of Psychiatry in Clinical Practice·Burcu GoksanOguz Karamustafalioglu
Jan 21, 2016·Behavioral Sleep Medicine·Ariel B NeikrugJason C Ong
Jan 28, 2012·Sleep Medicine·Alcinda DavidTeresa Paiva
Jun 22, 2011·Sleep Medicine·H A Droogleever FortuynS Overeem
Aug 6, 2009·Progress in Neurobiology·Mortimer Mamelak
Jun 6, 2009·Sleep Medicine Reviews·Virginie BayonPierre Philip
May 4, 2007·Sleep Medicine·Michael Thorpy
May 22, 2007·Sleep Medicine·Richard DodelGeert Mayer
Jun 2, 2009·Journal of the American Geriatrics Society·Harrison G BloomPhyllis C Zee
Aug 17, 2006·Acta Neurologica Scandinavica·S ErvikG Strand
Feb 16, 2008·Journal of Sleep Research·Francesca IngravalloGiuseppe Plazzi
Mar 1, 2008·Movement Disorders : Official Journal of the Movement Disorder Society·Leonardo SerraGiuseppe Plazzi
Mar 19, 2013·Journal of Sleep Research·Gianina LucaUNKNOWN European Narcolepsy Network
Jan 6, 2010·Acta Neurologica Scandinavica·P Jennum, J Kjellberg
Jun 13, 2014·CNS Neuroscience & Therapeutics·Clara O InocentePatricia Franco
Jun 1, 2015·Sleep Medicine·Gislene Serafim IatalleseFernando Morgadinho Coelho
Dec 2, 2014·Sleep Medicine·Laura ZamarianBirgit Frauscher
Sep 21, 2010·Sleep Medicine·Luca VignatelliRoberto D'Alessandro
May 5, 2012·PloS One·Sophie BayardYves Dauvilliers
Sep 26, 2016·Sleep Medicine·Petra KovalskáKarel Šonka
Jun 12, 2008·Arquivos de neuro-psiquiatria·Heloísa RovereRubens Reimão
Apr 12, 2012·Journal of Dental Research·J WangY F Lin
May 6, 2011·The Journal of Nervous and Mental Disease·Cecilia O JaraPeter Geisler
Jan 24, 2019·The Journal of Nervous and Mental Disease·Alberto RaggiRaffaele Ferri
Jun 16, 2009·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·Luohua JiangUNKNOWN AI-SUPERPFP Team
Jan 1, 2010·Sleep and Biological Rhythms·Christopher E KlineShawn D Youngstedt
Feb 7, 2008·The Cochrane Database of Systematic Reviews·L VignatelliL Candelise
Sep 19, 2018·Alimentary Pharmacology & Therapeutics·Jessica K DysonUNKNOWN UK-AIH Consortium
Jan 29, 2019·Journal of Human Kinetics·Dariusz JastrzębskiDariusz Ziora
Aug 2, 2018·Chronobiology International·Momoko KayabaYuichi Inoue
Aug 18, 2020·Journal of Clinical Sleep Medicine : JCSM : Official Publication of the American Academy of Sleep Medicine·Jason C OngCameron Moore
Jul 7, 2020·Arquivos de neuro-psiquiatria·Renata Carvalho CremaschiFernando Morgadinho Coelho
Jun 30, 2010·Revista brasileira de psiquiatria : orgão oficial da Associação Brasileira de Psiquiatria, Asociación Psiquiátrica de la América Latina·Flávio AlóeStella Márcia Azevedo Tavares

❮ Previous
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