Health-related quality of life in patients with major salivary gland carcinoma

European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
Christoph BeckerKilian Konrad Kenjiro Dahlem

Abstract

To evaluate the health-related quality of life (QOL) in patients with major salivary gland carcinoma (MSGC). 45 patients with MSGC completed the University of Washington Quality of Life (UWQOL) questionnaire. Results and factors influencing quality of life were analyzed using Mann-Whitney U test. 24 patients were male, 21 patients were female, and median age was 57 years. 33 patients presented with early stage (UICC stage I or II) cancer. All patients had surgery as initial therapy. The UWQOL domains with the worst results were 'appearance', 'activity' and 'anxiety'. Factors influencing QOL were sex, tumor stage, comorbidities, follow-up time, tumor grade, postoperative radiation therapy and facial nerve dysfunction. Diagnosis and treatment of MSGC has influence on overall QOL. Postoperative radiation has the greatest impact on QOL. This is one of the largest study evaluating QOL in patients with salivary gland carcinoma using the UWQOL.

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Citations

Dec 29, 2020·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Sati AkbabaNils H Nicolay
Apr 27, 2021·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Jessica L GeigerPatrick Ha
May 30, 2021·The Laryngoscope·Jovanna ThielkerOrlando Guntinas-Lichius

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