Health-related quality of life in patients with esophageal cancer or precancerous lesions assessed by EQ-5D: A multicenter cross-sectional study.

Thoracic Cancer
Youqing WangJie He

Abstract

We aimed to obtain a set of health state utility scores of patients with esophageal cancer (EC) and precancerous lesions in China, and to explore the influencing factors of health-related quality of life (HRQoL). A hospital-based multicenter cross-sectional study was conducted. From 2013 to 2014, patients with EC or precancerous lesions were enrolled. HRQoL was assessed using a European quality of life-5 dimension (EQ-5D-3L) instrument. Multivariable linear regression analysis was performed to explore the influencing factors of the EQ-5D utility scores. A total of 2090 EC patients and 156 precancer patients were included in the study. The dimension of pain/discomfort had the highest rate of self-reported problems, 60.5% in EC and 51.3% in precancer patients. The mean visual analog scale (VAS) score for EC and precancer patients were 68.4 ± 0.7 and 64.5 ± 3.1, respectively. The EQ-5D utility scores for EC and precancer patients were estimated as 0.748 ± 0.009 and 0.852 ± 0.022, and the scores of EC at stage I, stage II, stage III, and stage IV were 0.693 ± 0.031, 0.747 ± 0.014, 0.762 ± 0.015, and 0.750 ± 0.023, respectively. According to the multivariable analyses, the factors of region, occupation, household income in 2012, hea...Continue Reading

References

Jun 1, 1992·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·D Osoba
Jun 1, 1992·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·S G NayfieldB J Hailey
Jan 1, 1995·The Australian and New Zealand Journal of Surgery·I O'RourkeD C Johnson
Apr 15, 1993·Annals of Internal Medicine·G H GuyattD L Patrick
Oct 1, 1996·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·J M BlazebyJ R Farndon
Jun 24, 1998·Journal of the National Cancer Institute·M L Essink-BotF H Schröder
Feb 9, 1986·Journal of Health Economics·G W Torrance
Jun 23, 2001·The American Journal of Gastroenterology·S LevensteinD A Drossman
Aug 9, 2001·Annals of Medicine·R Rabin, F de Charro
Nov 1, 2002·Medical Care·Daniel PolskyKevin A Schulman
Jun 8, 2004·The American Journal of Gastroenterology·Stephan M WildiMichael B Wallace
Aug 4, 2004·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·Marjolein Y V HomsUNKNOWN Dutch SIREC Study Group
May 10, 2007·PharmacoEconomics·A Simon PickardAndrew Lloyd
Dec 25, 2007·Health and Quality of Life Outcomes·A Simon PickardDavid Cella
Jan 22, 2009·The Journal of Thoracic and Cardiovascular Surgery·Najib SafieddineGail Darling
May 9, 2009·International Journal of Behavioral Medicine·Maria Cristina CanavarroTiago Paredes
Nov 27, 2009·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Hui-Chu LangChung-Fu Lan
Feb 20, 2010·European Archives of Psychiatry and Clinical Neuroscience·Camila MoraesCassio M C Bottino
Apr 7, 2010·Annals of Surgical Oncology·Thomas W RiceValerie W Rusch
Jul 10, 2010·Value in Health : the Journal of the International Society for Pharmacoeconomics and Outcomes Research·Eun-Jeong Kang, Su-Kyoung Ko
Nov 3, 2010·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·Sun SunKristina Burström
Dec 7, 2010·The European Journal of Health Economics : HEPAC : Health Economics in Prevention and Care·Nick KontodimopoulosDimitris Niakas
Dec 8, 2010·Diabetes Research and Clinical Practice·Sang Shin ParkSang Woo Oh
Aug 10, 2012·PloS One·Jian-Bing WangPaolo Boffetta
Jan 16, 2013·Asian Pacific Journal of Cancer Prevention : APJCP·Jian-Ying LinXiu-Min Li
Nov 14, 2013·Japanese Journal of Clinical Oncology·Hideomi YamashitaKeiichi Nakagawa
Jun 28, 2014·Value in Health : the Journal of the International Society for Pharmacoeconomics and Outcomes Research·Mark OppeFrank de Charro
Aug 17, 2014·Value in Health : the Journal of the International Society for Pharmacoeconomics and Outcomes Research·Gordon G LiuNan Luo
Sep 23, 2014·International Journal of Cancer. Journal International Du Cancer·Hongmei ZengXue Qin Yu
Oct 20, 2014·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·J DielsR N Dass
Apr 22, 2015·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·Renata de Miranda MenezesPaul Kind
Feb 11, 2016·Clinical Drug Investigation·Miguel A RuizJavier Rejas
Nov 16, 2016·Health and Quality of Life Outcomes·Chi-Yang ChangJaw-Town Lin
Apr 15, 2017·Value in Health : the Journal of the International Society for Pharmacoeconomics and Outcomes Research·Nan LuoKim Rand-Hendriksen
Apr 28, 2017·Annals of Cardiothoracic Surgery·Bo NingMohamed O Othman

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Citations

Sep 19, 2020·Cost Effectiveness and Resource Allocation : C/E·Yuanyuan LiHengjin Dong
Jan 8, 2021·International Journal for Equity in Health·Sha LaiXiaolong Zhang

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