Health-Related Quality of Life in Thoracic Aortic Disease: Part I. Cases Managed Non-operatively

Aorta : Official Journal of the Aortic Institute at Yale-New Haven Hospital
Christian Olsson, Anders Franco-Cereceda

Abstract

The health-related quality of life (HRQOL) in subjects with chronic thoracic aortic disease (TAD) not scheduled for intervention has not been previously reported. Such information may aid counseling, management, and clinical decision-making. We report HRQOL in TAD, its main subtypes (aneurysm versus dissection and proximal versus distal), compare it to a reference group from the general population, and explore independent predictors. The short-form 36-item (SF-36) questionnaire was used, as part of a self-reporting health survey, to measure HRQOL in eight domains and a physical component summary (PCS) and a mental component summary (MCS) score. Median differences (Δ) between the component summary scores and a sex- and age-matched reference group from the general population were the primary outcome measures. Multivariable techniques were used to evaluate independent predictors. In 178 TAD subjects, the HRQOL was reduced (versus the reference group) in the PCS, Δ -6.4 [95% confidence limits -8.8, -4.0] and in three out of eight SF-36 domains: physical functioning (PF), Δ -10 [-15, -4.5]; physical role (RP), Δ -25 [-34, -16]; general health (GH), Δ -5.0 [-9.7, -0.27]. There were no statistically significant differences in HRQOL sc...Continue Reading

Citations

Jun 24, 2014·Noise & Health·Monika NitschkeDino L Pisaniello
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Sep 25, 2020·Scandinavian Journal of Caring Sciences·Mette JönssonPernille Palm
Mar 20, 2019·Expert Review of Cardiovascular Therapy·Carlijn G E ThijssenJolien W Roos-Hesselink

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