Health-related quality of life of HIV-infected adults receiving combination antiretroviral therapy in Addis Ababa

AIDS Care
Legese A MekuriaPythia T Nieuwkerk

Abstract

Health-related quality of life (HRQoL) is an important outcome measure among HIV-infected patients receiving combination antiretroviral therapy (cART), but has not been studied extensively in resource-limited settings. Insight in the predictors or correlates of poor HRQoL may be helpful to identify patients most in need of additional support and to design appropriate interventions. A cross-sectional study was conducted between September 2012 and April 2013 in 10 healthcare facilities in Addis Ababa, Ethiopia. Patients who were at least 6 months on cART were randomly selected and individual patient data were retrieved from medical records. HRQoL was measured by the WHOQoL-HIVBREF, depressive-symptoms by the Kessler-6 scale, and stigma by the Kalichman internalized AIDS-related stigma scale. Multivariate linear regression analysis was carried-out to examine associations between HRQoL and the other variables. A total of 664 patients (response-rate 95%) participated in the study. A higher level of depressive-symptoms was most strongly and consistently associated with a lower HRQoL, both in terms of the magnitude of the relationship and in the number of HRQoL domains associated with it. Also, a higher level of HIV-stigma was associa...Continue Reading

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Citations

May 26, 2016·The Journal of the Association of Nurses in AIDS Care : JANAC·Natthani MeemonThomas T H Wan
Oct 3, 2019·AIDS Research and Therapy·Ahmad AliyuManhattan Charurat
Jun 7, 2020·Health and Quality of Life Outcomes·Moses K NyongesaAmina Abubakar
Dec 23, 2016·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·Nahed S AlsayedJudith A Erlen
Jun 7, 2017·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·Marcin RzeszutekEwa Firląg-Burkacka
Aug 31, 2017·Health and Quality of Life Outcomes·Mekuriaw AlemayehuAbebaw Gebayehu
Jul 7, 2017·Open Forum Infectious Diseases·A David PaltielRochelle P Walensky
Feb 27, 2021·Health and Quality of Life Outcomes·Fikadu Tadesse Nigusso, Azwihangwisi Helen Mavhandu-Mudzusi
Mar 19, 2019·Journal of Affective Disorders·Alexandra S RooneyUNKNOWN HIV Neurobehavioral Research Program
Jun 3, 2021·International Journal of Environmental Research and Public Health·Chia-Hui YuSu-Fen Cheng
Jul 2, 2021·BMC Public Health·Sri Sunaringsih Ika WardojoKun-Yang Chuang

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