PMID: 9551279Apr 29, 1998Paper

Health services research clinical trials: issues in the evaluation of economic costs and benefits

Controlled Clinical Trials
L M Manheim

Abstract

The costs and benefits of treatment interventions are difficult both to conceptualize and to measure. This paper discusses methodologic issues that arise in measuring costs, distinguishing between social costs and transfer payments, measuring the value of life and limb, and assessing the meaning of cost differences. Long-run vs. short-run costs and average vs. marginal costs are considered. Sensitivity analysis to assess the robustness of results to alternative assumptions is stressed. Cost-benefit and cost-effectiveness analyses are seen as important in assessing the policy implications of clinical trials; a proper cost-benefit analysis allows the reader to understand how results relate to the assumptions made in the analyses.

References

Mar 7, 1996·The New England Journal of Medicine·R M Williams
Oct 16, 1996·JAMA : the Journal of the American Medical Association·M C WeinsteinL B Russell
Apr 29, 1998·Controlled Clinical Trials·W G HendersonD Deykin

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Citations

May 25, 2002·Aging Clinical and Experimental Research·P Werner, I Vered
Nov 30, 2002·Journal of Pain and Symptom Management·Craig Gannon, Penny McNamara
Feb 26, 2010·Psychotherapy Research : Journal of the Society for Psychotherapy Research·Merton S Krause, Wolfgang Lutz
Aug 30, 2001·Radiology·UNKNOWN Evidence-Based Radiology Working Group
Sep 23, 2003·Cost Effectiveness and Resource Allocation : C/E·Archana B PatelManwar S Rawat
Jun 29, 2002·Risk Analysis : an Official Publication of the Society for Risk Analysis·H Christopher Frey, Sumeet R Patil
Nov 28, 2012·Journal of Clinical Epidemiology·Archana B PatelMichael J Dibley
Oct 9, 2008·Journal of Nursing Scholarship : an Official Publication of Sigma Theta Tau International Honor Society of Nursing·Anne H SkellyDorothy Burns
Nov 28, 2008·Clinical Rheumatology·Sayed Javad MousaviAli Montazeri
Jun 26, 2007·European Journal of Cancer Care·A SalaR Barr
Jan 11, 2013·Injury Prevention : Journal of the International Society for Child and Adolescent Injury Prevention·Julie A MyttonBarbara Potter

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