Health state utilities in patients with advanced non-small-cell lung cancer in China

Journal of Comparative Effectiveness Research
Yunjie ShenJun Zhu

Abstract

Non-small-cell lung cancer (NSCLC) is a leading global health threat that impairs patient health outcomes. Health state utilities are fundamental values in economic evaluation and significantly vary across countries. Given the scarce data on the Chinese population, the current study measured utility values in the Chinese patients with NSCLC. This study was conducted as a cross-sectional survey of patients with advanced NSCLC at the Shanghai Chest Hospital. Utility values were assessed using the EuroQol five-dimension (EQ-5D) instrument and scored based on the Chinese-specific value algorithm. Predictors of utility values were examined using a subgroup analysis and a multiple regression model. The mean EQ-5D utility value of recruited patients was 0.814. The regression analysis revealed that tumor stage, treatment regimen and line of therapy were the potential predictors of utility values. This study provides the Chinese-specific health utility data for advanced NSCLC using the EQ-5D.

References

Nov 21, 1997·Medical Care·P Dolan
Aug 9, 2001·Annals of Medicine·R Rabin, F de Charro
Apr 16, 2003·Annals of Internal Medicine·Mitchell H Katz
May 1, 2007·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·Mathias LidgrenClas Rehnberg
Jan 9, 2008·Value in Health : the Journal of the International Society for Pharmacoeconomics and Outcomes Research·Adrian R LevyAndrew H Briggs
May 10, 2008·Lung Cancer : Journal of the International Association for the Study of Lung Cancer·Scott DoyleMel Walker
Oct 23, 2008·Health and Quality of Life Outcomes·Beenish NafeesJessamy Watkins
Jul 9, 2009·The European Journal of Health Economics : HEPAC : Health Economics in Prevention and Care·John E BrazierDonna Louise Rowen
May 8, 2010·Medical Decision Making : an International Journal of the Society for Medical Decision Making·Julie Sturza
Sep 24, 2010·Thorax·Janneke P C GruttersMadelon Pijls-Johannesma
Apr 21, 2011·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·Hong-Mei WangWen-Wen Gu
Dec 19, 2012·Health and Quality of Life Outcomes·Seon Ha KimJin-Hee Ahn
Jun 22, 2013·Journal of Thoracic Oncology : Official Publication of the International Association for the Study of Lung Cancer·Christos ChouaidPaul L R Mitchell
Aug 17, 2014·Value in Health : the Journal of the International Society for Pharmacoeconomics and Outcomes Research·Gordon G LiuNan Luo
May 15, 2015·Health and Quality of Life Outcomes·Minmin WuBiao Xu
Sep 16, 2015·Cancers·Vishal BoolellVinod Ganju
Dec 17, 2015·Advances in Experimental Medicine and Biology·Lindsey A TorreAhmedin Jemal
Dec 20, 2015·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·Frédéric FiteniVirginie Westeel
Mar 19, 2016·Asia-Pacific Journal of Clinical Oncology·Beenish NafeesMaria Lorenzo
Jul 15, 2016·Translational Lung Cancer Research·Cecilia Zappa, Shaker A Mousa

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Citations

Jun 15, 2021·The European Journal of Health Economics : HEPAC : Health Economics in Prevention and Care·Mir-Masoud PourrahmatKaren C Chung

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