Health State Utility Impact of Breast Cancer in U.S. Women Aged 18-44 Years

American Journal of Preventive Medicine
Derek S BrownJuan L Rodriguez

Abstract

Breast cancer affects women's health-related quality of life negatively, but little is known about how breast cancer affects this in younger women aged 18-44 years. This study measures preference-based health state utility (HSU) values, a scaled index of health-related quality of life for economic evaluation, for younger women with breast cancer and compares these values with same-age women with other cancers and older women (aged ≥45 years) with breast cancer. Data from the 2009 and 2010 Behavioral Risk Factor Surveillance System were analyzed in 2014. The sample included 218,852 women; 7,433 and 18,577 had histories of breast and other cancers. HSU values were estimated using Healthy Days survey questions and a published mapping algorithm. Linear regression models for HSU were estimated by age group (18-44 and ≥45 years). The adjusted breast cancer HSU impact was four times larger for younger women than for older women (-0.097 vs -0.024, p<0.001). For younger women, the effect of breast cancer on HSU was 70% larger than that of other cancers (-0.097 vs -0.057, p=0.024). Younger breast cancer survivors reported lower HSU values than older survivors, highlighting the impact of breast cancer on the physical and mental health of ...Continue Reading

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Citations

Jan 19, 2016·American Journal of Preventive Medicine·Donatus U Ekwueme, Justin G Trogdon
Mar 10, 2020·Paediatric and Perinatal Epidemiology·Tamara S ReynoldsAmanda E Toland
Jul 14, 2017·Breast Cancer Research and Treatment·Justin G TrogdonBenjamin T Allaire
Aug 25, 2019·Applied Health Economics and Health Policy·Renée Else MichelsMarieke Krol
Dec 19, 2020·International Journal of Environmental Research and Public Health·Ji Ryoun GongSeungJin Bae

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