Health Status and Psychological Distress in Patients with Non-compaction Cardiomyopathy: The Role of Burden Related to Symptoms and Genetic Vulnerability

International Journal of Behavioral Medicine
Corline BrouwersSusanne S Pedersen

Abstract

Non-compaction cardiomyopathy (NCCM) is a cardiomyopathy characterized by left ventricular tribeculae and deep intertrabecular recesses. Because of its genetic underpinnings and physical disease burden, noncompaction cardiomyopathy is expected to be associated with a lower health status and increase in pscyhological distress. This study determined the health status and psychological distress in NCCM patients. We also examined the potential contribution of genetic predisposition and cardiac symptoms to health status and distress in NCCM, by comparing NCCM patients with (1) patients with familial hypercholesterolemia (FH) and (2) patients with acquired dilated cardiomyopathy (DCM). Patients were recruited from the Erasmus Medical Center, Rotterdam, The Netherlands. Using a case-control design, NCCM patients (N = 45, mean age 46.7 ± 15.1 years, 38 % male) were compared with 43 FH patients and 42 DCM patients. Outcome measures were health status (Short Form Health Survey-12), anxiety (Generalized Anxiety Disorder 7-item scale) and depression (Patient Health Questionnaire 9-item scale). NCCM patients showed significantly worse health status (Physical Component Score F(1,84) = 9.58, P = .003; Mental Component Score F(1,84) = 16.65, P...Continue Reading

References

Feb 1, 1994·Journal of Clinical Epidemiology·M J Irvine, A G Logan
Mar 10, 1997·Archives of Internal Medicine·L K AndersenO Faergeman
Jul 9, 1999·American Journal of Medical Genetics·R M PauliG S Sekhon
Apr 16, 2002·Journal of Internal Medicine·G HollmanA G Olsson
May 24, 2006·Archives of Internal Medicine·Robert L SpitzerBernd Löwe
Oct 17, 2007·American Journal of Medical Genetics. Part a·Marion McAllisterRhona MacLeod
Feb 19, 2008·Genetics in Medicine : Official Journal of the American College of Medical Genetics·Jodie InglesChristopher Semsarian
Feb 27, 2009·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·Floortje MolsNina Kupper
Mar 3, 2009·American Journal of Medical Genetics. Part a·Imke ChristiaansEllen M A Smets
Jun 10, 2010·Circulation. Cardiovascular Genetics·Yvonne M HoedemaekersDanielle F Majoor-Krakauer
Jun 16, 2010·Heart Failure Reviews·Josef Finsterer
Sep 28, 2010·Heart Failure Clinics·Jeffrey A Towbin
Nov 27, 2010·Heart Failure Clinics·Daniëlle E P VerbeekPeter de Jonge
Dec 21, 2011·CMAJ : Canadian Medical Association Journal = Journal De L'Association Medicale Canadienne·Laura ManeaDean McMillan
May 5, 2012·Genetics in Medicine : Official Journal of the American College of Medical Genetics·Jodie InglesChristopher Semsarian

❮ Previous
Next ❯

Citations

Aug 23, 2016·Case Reports in Cardiology·Josef Finsterer, Claudia Stöllberger

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cardiomyopathy

Cardiomyopathy is a disease of the heart muscle, that can lead to muscular or electrical dysfunction of the heart. It is often an irreversible disease that is associated with a poor prognosis. There are different causes and classifications of cardiomyopathies. Here are the latest discoveries pertaining to this disease.

Related Papers

JBR-BTR : Organe De La Société Royale Belge De Radiologie (SRBR) = Orgaan Van De Koninklijke Belgische Vereniging Voor Radiologie (KBVR)
H K KokP Ma
Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography
Warren G Guntheroth
Cardiovascular Diagnosis and Therapy
Kamal ShemisaJulio Barcena
© 2021 Meta ULC. All rights reserved