Health status of young children during therapy for advanced neuroblastoma

Pediatric Blood & Cancer
Paul C NathanRonald D Barr

Abstract

The purpose of this study was to describe the health status experienced by young children during various phases of therapy for advanced neuroblastoma. Nineteen patients aged 2.00-4.99 years at the time of diagnosis of neuroblastoma (stages 3 or 4) who received active therapy between 1996 and 2000 were enrolled on the study. Their parents provided proxy assessments of their health status at a maximum of 10 assessment points during therapy using the Comprehensive Health Status Classification System for Pre-school Children (CHSCS-PS), which assesses level of function on 10 separate health domains. Eighty-six assessment questionnaires were completed. Maximum morbidity was reported immediately following diagnosis and in the 2-3 weeks following bone marrow transplantation. The greatest morbidity was observed in the pain, self-care, mobility, and emotion domains. In addition to facing a high risk of mortality, young children being treated for advanced neuroblastoma also experience considerable morbidity.

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Citations

Sep 28, 2006·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·William Furlong, Ronald D Barr
Oct 19, 2006·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·Ka-Ming LauSing Kai Lo
Oct 29, 2010·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·Hein RaatJohan P Mackenbach
Feb 17, 2005·Pediatric Blood & Cancer·Caroline LaverdièreCharles A Sklar

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