Healthcare provider targeted interventions to improve medication adherence: systematic review and meta-analysis

International Journal of Clinical Practice
Vicki S ConnKeith C Chan

Abstract

This systematic review applied meta-analytic procedures to synthesise medication adherence (also termed compliance) interventions that focus on healthcare providers. Comprehensive searching located studies testing interventions that targeted healthcare providers and reported patient medication adherence behaviour outcomes. Search strategies included 13 computerised databases, hand searches of 57 journals, and both author and ancestry searches. Study sample, intervention characteristics, design and outcomes were reliably coded. Standardised mean difference effect sizes were calculated using random-effects models. Heterogeneity was examined with Q and I(2) statistics. Exploratory moderator analyses used meta-analytic analogue of ANOVA and regression. Codable data were extracted from 218 reports of 151,182 subjects. The mean difference effect size was 0.233. Effect sizes for individual interventions varied from 0.088 to 0.301. Interventions were more effective when they included multiple strategies. Risk of bias assessment documented larger effect sizes in studies with larger samples, studies that used true control groups (as compared with attention control), and studies without intention-to-treat analyses. Overall, this meta-anal...Continue Reading

References

Jun 17, 1974·JAMA : the Journal of the American Medical Association·R F Gillum, A J Barsky
Sep 10, 2002·Medical Care·M Robin DiMatteoThomas W Croghan
Sep 11, 2002·Patient Education and Counseling·Nicola Mead, Peter Bower
Dec 12, 2003·European Journal of Cardiovascular Nursing : Journal of the Working Group on Cardiovascular Nursing of the European Society of Cardiology·Sabina De Geest, Eduardo Sabaté
Jan 20, 2004·Patient Education and Counseling·Jane HarringtonStanton P Newman
May 17, 2005·Patient Education and Counseling·Kristina H JahngM Robin DiMatteo
Jan 19, 2006·Advances in Therapy·Kem P KruegerBill Felkey
Jan 25, 2006·The American Journal of Medicine·Hayden B BosworthEugene Z Oddone
Jun 23, 2006·BMJ : British Medical Journal·Scot H SimpsonJeffrey A Johnson
Mar 14, 2007·Journal of General Internal Medicine·Ira B WilsonDana Gelb Safran
Oct 31, 2008·Hypertension Research : Official Journal of the Japanese Society of Hypertension·Andreas ZellerPeter Tschudi
Nov 18, 2008·Patient Education and Counseling·Antoinette SchoenthalerGbenga Ogedegbe
Apr 28, 2009·Patient Education and Counseling·Alexis Arbuthnott, Donald Sharpe
Jul 9, 2009·Medical Care·Kelly B Haskard Zolnierek, M Robin Dimatteo
Aug 12, 2009·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·Bruce Bender
Jun 15, 2010·Patient Education and Counseling·Charitini Stavropoulou
Aug 3, 2010·Patient Education and Counseling·Christy J W LedfordBrian Keefe
Aug 20, 2010·Medical Care·Marie A Chisholm-BurnsTimothy Wunz
Sep 9, 2011·Neurology·C D BushnellUNKNOWN AVAIL Investigators
Jan 25, 2012·Annals of Behavioral Medicine : a Publication of the Society of Behavioral Medicine·Antoinette SchoenthalerGbenga Ogedegbe
Feb 1, 2012·AIDS and Behavior·M Barton LawsIra B Wilson
May 31, 2012·Journal of Health Care for the Poor and Underserved·Oni J BlackstockOladipo A Alao
Jun 1, 2012·Journal of the American Geriatrics Society·Derjung M TarnNeil S Wenger
Aug 24, 2013·The New England Journal of Medicine·Lisa Rosenbaum, William H Shrank

❮ Previous
Next ❯

Citations

Jul 16, 2015·Israel Journal of Health Policy Research·Lisa V Rubenstein
Mar 26, 2015·International Journal of Behavioral Medicine·Todd M RupparSabina M De Geest
Feb 25, 2017·The Journal of Neuroscience Nursing : Journal of the American Association of Neuroscience Nurses·Jennifer L WessolAn-Lin Cheng
Aug 26, 2015·Journal of Primary Care & Community Health·Maithe Enriquez, Vicki S Conn
Jul 20, 2019·International Journal of Rheumatic Diseases·Parvaneh HeidariKimberley Crawford
May 31, 2019·JBI Database of Systematic Reviews and Implementation Reports·Jacqueline RoseleurJonathan Karnon
Mar 1, 2020·International Journal of Environmental Research and Public Health·Gill RowlandsJoanne Protheroe
Nov 18, 2021·Journal of the International Association of Providers of AIDS Care·Juddy WachiraIra B Wilson

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

European Journal of Cardiovascular Nursing : Journal of the Working Group on Cardiovascular Nursing of the European Society of Cardiology
Todd M RupparJonathon Temple
© 2022 Meta ULC. All rights reserved