Healthy Adolescent Performance With Standardized Scoring Tables for the MATRICS Consensus Cognitive Battery: A Multisite Study

Schizophrenia Bulletin
Runar Elle SmelrorIngrid Agartz

Abstract

The aim of this study was to develop standardized scores and scoring tables for test performance in healthy adolescents for the Measurement and Treatment Research to Improve Cognition in Schizophrenia (MATRICS) Consensus Cognitive Battery (MCCB) for each year from 11 to 19 years of age, by sex, with T scores and percentile ranks. A total of 502 healthy participants (aged 11-19 years) from 7 cohorts from Ireland, Norway, Sweden, and United States, were included in this multisite study. Regression-predicted means for the MCCB tests, except the social cognition subtest, were calculated using the MCCB test scores as outcome variables and age, age2, sex, age × sex as predictors. The regression-predicted means for each combination of age and sex were added with the residuals from the entire cohort to yield the expected distribution of that group. Age effects were examined using regression models with age and age2 as predictors. Sex differences were examined using Student's t-tests. Significant positive age effects were found for all tests, except for the Brief Visuospatial Memory Test, revised (BVMT-R; measure of visual learning). Females performed significantly better than males on BACS Symbol coding (measure of speed of processing)...Continue Reading

References

Feb 1, 1997·Archives of General Psychiatry·J M GoldD R Weinberger
Sep 15, 1999·Journal of Clinical and Experimental Neuropsychology·P S Fastenau
Dec 16, 2003·Cognitive, Affective & Behavioral Neuroscience·Jennifer D Ryan, Neal J Cohen
Nov 29, 2005·Frontiers in Neuroendocrinology·Cheryl L Sisk, Julia L Zehr
Feb 24, 2006·Journal of Child Psychology and Psychiatry, and Allied Disciplines·Sarah-Jayne Blakemore, Suparna Choudhury
Jun 13, 2006·Molecular and Cellular Endocrinology·Jay N GieddGeorge P Chrousos
Sep 27, 2006·Archives of Clinical Neuropsychology : the Official Journal of the National Academy of Neuropsychologists·Alicia M NagleMarianna Walker
May 22, 2007·Journal of the International Neuropsychological Society : JINS·Deborah P WaberUNKNOWN Brain Development Cooperative Group
Jan 4, 2008·The American Journal of Psychiatry·Robert S KernStephen R Marder
Jan 4, 2008·The American Journal of Psychiatry·Keith H NuechterleinStephen R Marder
Sep 17, 2008·The World Journal of Biological Psychiatry : the Official Journal of the World Federation of Societies of Biological Psychiatry·Hee Jung NamKyung Sue Hong
Nov 13, 2008·Nature Reviews. Neuroscience·Tomás PausJay N Giedd
May 25, 2010·Human Brain Mapping·Sarah-Jayne BlakemoreRonald E Dahl
Jul 27, 2011·Proceedings of the National Academy of Sciences of the United States of America·Zdravko PetanjekIvica Kostovic
Dec 20, 2011·NeuroImage·Sarah-Jayne Blakemore
Mar 24, 2012·Journal of Clinical and Experimental Neuropsychology·Christine MohnBjørn Rishovd Rund
Oct 15, 2013·NeuroImage·Anne-Lise GoddingsSarah-Jayne Blakemore
Dec 11, 2013·Schizophrenia Research·George C NitzburgAnil K Malhotra

❮ Previous
Next ❯

Software Mentioned

SPSS Statistics
SPSS

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.