Hearing impairment in type 2 diabetics and patients with early diabetic nephropathy

Journal of Diabetes and Its Complications
Jianmin RenXiaoyan Xiao

Abstract

The study was to investigate the hearing function in subjects with non-diabetic nephropathy and diabetic nephropathy and analyze related clinical indexes of hearing impairment. We assessed the hearing function of 30 diabetics (DM group), 30 patients with early diabetic nephropathy (DN group) and 30 healthy subjects (NC group) using pure-tone audiometry, otoacoustic emissions, electronystagmography, caloric test and cervical vestibular evoked myogenic potential (VEMP). Pure-tone audiogram demonstrated a deficit at frequencies with elevated threshold in both DM and DN group (p < 0.05). DN group showed a significant deficit with elevated threshold at 250, 8000 Hz in left ear and 8000 Hz in right ear compared to those of DM group (p < 0.05). GHbA1c, waist and ACR were correlated with elevated thresholds. The DPOAE amplitudes of DN group were obviously smaller in the left ear (4 kHz) and right ear (0.75, 2, 4 kHz) while those of DM group were significantly smaller in the right ear (0.75, 4 kHz) than controls (p < 0.05). A larger proportion of subjects with vestibular dysfunction and VEMP response absence were observed in DN group. Type 2 DM and DN patients have shown clinical hearing impairment and vestibular dysfunction. GHbA1c, wa...Continue Reading

Citations

Dec 19, 2018·Gerontology & Geriatric Medicine·Andrzej LewandowiczPaweł Piątkiewicz
Aug 27, 2019·European Journal of Pharmacology·Rubiya KhursheedKamal Dua
Nov 5, 2020·Evidence-based Complementary and Alternative Medicine : ECAM·Lin RenFeng Qin
Aug 9, 2020·Clinical and Experimental Otorhinolaryngology·Aida DoostkamKazem Zarei

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