Abstract
To investigate the middle and inner ear involvement in patients with progressive systemic sclerosis (PSS). We prospectively evaluated 34 PSS patients. All patients underwent a complete ear-nose-throat physical examination and audiological evaluation with pure tone, impedance, and speech audiometry. In addition, systemic manifestations of the disease and drug therapy were recorded. Finally, all patients were tested for the presence of autoantibodies. The results were compared with those of 45 age-matched healthy subjects. We found a sensorineural hearing loss in 20% and mixed type hearing loss in 3.3% of the patients. There was no correlation of hearing loss with age, systemic manifestations of the disease, presence of autoantibodies, and drug therapy. Ten percent of the patients had patulous eustachian tubes. One fourth of PSS patients had a hearing loss affecting the middle and mainly the high frequencies. This is a lower percentage than that reported by other investigators. A significant prevalence of bilateral patulous eustachian tubes was noticed as well. Further investigation is needed for a better understanding of the mechanism of ear damage in PSS patients.
References
Jan 1, 1972·Scandinavian Journal of Rheumatology·T Heyworth, S P Liyanage
May 1, 1972·Annals of the Rheumatic Diseases·C J GoodwillR P Jones
Feb 1, 1970·Archives of Neurology·R M Gordon, A Silverstein
Mar 1, 1980·Medicine·R D TeasdallL E Shulman
Jul 1, 1982·The Laryngoscope·A D KornblutA S Fauci
May 1, 1980·Arthritis and Rheumatism
Jan 1, 1981·Bulletin on the Rheumatic Diseases
Aug 1, 1995·The Journal of Laryngology and Otology·I KastanioudakisM H Moustopoulos
Jul 1, 1994·ORL; Journal for Oto-rhino-laryngology and Its Related Specialties·S BerrettiniG Segnini
Citations
May 13, 2010·Rheumatology International·Katarzyna MaciaszczykTomasz Durko
Jun 4, 2008·Medicine·Juan C Amor-DoradoMiguel A Gonzalez-Gay
Jun 10, 2006·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Rosamaria SantarelliEdoardo Arslan
Feb 9, 2008·Critical Reviews in Toxicology·Perrine Hoet, Dominique Lison
Feb 24, 2009·La Revue de médecine interne·B HervierM Hamidou
Nov 18, 2003·Clinical Otolaryngology and Allied Sciences·J Mathews, B N Kumar
Sep 16, 2011·Scandinavian Journal of Rheumatology·T A MonteiroL G E Vasconcelos
Sep 16, 2011·Otolaryngologia polska. The Polish otolaryngology·Katarzyna MaciaszczykMagdalena Józefowicz-Korczyńska
Feb 1, 2014·Medical Hypotheses·Pulukool Sandhya, Debashish Danda
Nov 13, 2014·CoDAS·Maysa Bastos Rabelo, Ana Paula Corona
Aug 18, 2009·The Journal of Rheumatology·Agota HajasEdit Bodolay
Jan 18, 2006·Current Opinion in Neurology·Charlotte Agrup, Linda M Luxon
Dec 14, 2017·CoDAS·Julia de Souza Pinto Valente, Ana Paula Corona
Jun 4, 2018·Clinical Rheumatology·S ShenavandehA Zare
Feb 28, 2019·CoDAS·Marília Mendes SilvaAna Paula Corona
Apr 27, 2018·Vestnik otorinolaringologii·I V Savenko, M Yu Boboshko
Apr 28, 2021·Curēus·Renata RibeiroJosé Delgado Alves