Hearing preservation in patients with unilateral vestibular schwannoma who undergo stereotactic radiosurgery: Reinterpretation of the auditory brainstem response

Cancer
Jung Ho HanHee-Won Jung

Abstract

The objective of this study was to identify the prognostic factors for hearing preservation that would allow the more accurate stratification of patients who undergo stereotactic radiosurgery (SRS) for unilateral, sporadic vestibular schwannoma (VS). In total, 119 patients with VS who had serviceable hearing underwent SRS as primary treatment. The mean (±standard deviation) patient age was 48 ± 11 years, and the mean (±standard deviation) follow-up duration was 55.2 ± 35.7 months. The median marginal radiotherapy dose was 12.0 grays (Gy), and the mean (±standard deviation) tumor volume was 1.95 ± 2.24 cm(3) . The mean (±standard deviation) pure tone average (PTA) score was 26 ± 12 decibels (dB) (range, 4-50 dB), and the mean (±standard deviation) maximum speech discrimination score was 91 ± 12% (range, 52-100%). The mean (±standard deviation) baseline values for the interlatency (IL) of waves I and III (IL I-III) and the IL of waves I through V (IL I-V) on auditory brainstem response were 2.58 ± 0.60 milliseconds (mS) (range, 1.92-4.30 mS) and 4.80 ± 0.61 mS (range, 3.80-6.40 mS), respectively. In multivariate analysis, the PTA score and IL I-V were significant and independent prognostic factors (hazard ratio, 1.072; 95% confid...Continue Reading

References

Oct 1, 1986·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·H SilversteinT Haberkamp
Jan 1, 1988·The Annals of Otology, Rhinology, and Laryngology·G Gardner, J H Robertson
Jun 25, 1998·Archives of Otolaryngology--head & Neck Surgery·M O FergusonH C Pillsbury
May 4, 2000·Journal of Neurosurgery·D PrasadL Steiner
May 4, 2000·Journal of Neurosurgery·M Samii, C Matthies
Sep 25, 2001·Otology & Neurotology : Official Publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology·B BadieE J Hadar
Nov 15, 2002·Archives of Otolaryngology--head & Neck Surgery·Francesco OttavianiEnrico Motti
Feb 9, 2006·International Journal of Radiation Oncology, Biology, Physics·Stephanie E CombsDaniela Schulz-Ertner
Nov 24, 2006·Journal of Neurosurgery·William A FriedmanFrank J Bova
Mar 24, 2007·International Journal of Radiation Oncology, Biology, Physics·Rahul ChopraJohn C Flickinger
Jul 12, 2008·Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia·Yoshiyasu IwaiTsunemasa Aiba
Oct 22, 2008·Otology & Neurotology : Official Publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology·John M LasakGrant P Rine
Oct 25, 2008·Progress in Neurological Surgery·Seiji FukuokaHirohiko Nakamura
Dec 6, 2008·Neurosurgery·Ajay NiranjanL Dade Lunsford
Oct 1, 2007·Journal of Korean Neurosurgical Society·Kang-Min KimDong Gyu Kim
Mar 17, 2009·Journal of Neurosurgery·Hideyuki KanoL Dade Lunsford
Mar 19, 2009·Journal of Cancer Research and Therapeutics·Maria-Aggeliki KalogeridiGeorge Pissakas
Mar 24, 2009·Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia·Isaac YangAndrew T Parsa
Sep 15, 2009·Journal of Neurosurgery·Isaac YangAndrew T Parsa
Dec 3, 2009·Neurosurgical Focus·Alberto FranzinPietro Mortini
Jan 9, 2010·Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia·Chang-Hyun KimJung-Il Lee
Jan 26, 2010·Journal of Neurosurgery·Erin S MurphyJohn H Suh

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Citations

Feb 16, 2016·Neurologia Medico-chirurgica·Ayako HoribaYoshikazu Okada
Mar 22, 2018·Otology & Neurotology : Official Publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology·Vinay PrabhuGirish M Fatterpekar
Jan 18, 2018·Otology & Neurotology : Official Publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology·Adam R CoughlinSamuel P Gubbels
Apr 21, 2012·Pharmacogenomics·Jonathan KrellJustin Stebbing
Oct 16, 2020·Otology & Neurotology : Official Publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology·Dennis I BojrabDennis I Bojrab

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