Heart Failure and Cognitive Impairment in the Atherosclerosis Risk in Communities (ARIC) Study

Journal of General Internal Medicine
Lucy S WittPatricia P Chang

Abstract

Previous studies suggest that heart failure (HF) is an independent risk factor for cognitive decline. A better understanding of the relationship between HF, cognitive status, and cognitive decline in a community-based sample may help clinicians understand disease risk. To examine whether persons with HF have a higher prevalence of cognitive impairment and whether persons developing HF have more rapid cognitive decline. This observational cohort study of American adults in the Atherosclerosis Risk in Communities (ARIC) study has two components: cross-sectional analysis examining the association between prevalent HF and cognition using multinomial logistic regression, and change over time analysis detailing the association between incident HF and change in cognition over 15 years. Among visit 5 (2011-2013) participants (median age 75 years), 6495 had neurocognitive information available for cross-sectional analysis. Change over time analysis examined the 5414 participants who had cognitive scores and no prevalent HF at visit 4 (1996-1998). The primary outcome was cognitive status, classified as normal, mild cognitive impairment [MCI], and dementia on the basis of standardized cognitive tests (delayed word recall, word fluency, an...Continue Reading

References

Oct 29, 1997·Journal of Neurology, Neurosurgery, and Psychiatry·G ZuccalàR Bernabei
Jan 10, 2001·Neurology·D KnopmanUNKNOWN Atherosclerosis Risk in Communities (ARIC) Study Investigators
Jul 3, 2003·The Journal of Cardiovascular Nursing·Susan J Bennett, Mary Jane Sauvé
May 4, 2005·The American Journal of Medicine·Giuseppe ZuccalàRoberto Bernabei
Feb 14, 2006·Neurobiology of Aging·Angela L JeffersonRonald A Cohen
Apr 25, 2006·The Annals of Thoracic Surgery·Ralph J PetrucciJagat Narula
Dec 19, 2006·European Journal of Heart Failure·Raymond L C VogelsHenry C Weinstein
Aug 31, 2007·Journal of the American Geriatrics Society·Raymond L C VogelsHenry C Weinstein
Apr 26, 2008·The Journal of Cardiovascular Nursing·Susan J Pressler
Sep 6, 2011·Age and Ageing·Kathleen M HaydenRichard N Jones
Dec 28, 2011·International Journal of Behavioral Medicine·Jenny M CundiffCynthia A Berg
Jul 11, 2013·Circulation. Cardiovascular Quality and Outcomes·Alexandra M HajdukJane S Saczynski
Apr 2, 2014·Circulation·Kristine YaffeStephen Sidney
Apr 25, 2014·Alzheimer Disease and Associated Disorders·Andrea L C SchneiderThomas H Mosley
Apr 29, 2015·Journal of Neurology, Neurosurgery, and Psychiatry·Saira Saeed MirzaM Arfan Ikram
Dec 8, 2015·JAMA : the Journal of the American Medical Association·Arthur M FeldmanSteven T DeKosky
Jan 27, 2016·Circulation·UNKNOWN Writing Group MembersUNKNOWN Stroke Statistics Subcommittee
Mar 8, 2016·Alzheimer's & Dementia : Diagnosis, Assessment & Disease Monitoring·David S KnopmanThomas H Mosley
Aug 16, 2016·Alzheimer's & Dementia : the Journal of the Alzheimer's Association·Saira Saeed MirzaHenning Tiemeier
Oct 28, 2016·Arteriosclerosis, Thrombosis, and Vascular Biology·Behnam SabayanLenore J Launer
Nov 20, 2016·Journal of Cardiac Failure·Jan BresslerThomas H Mosley
May 26, 2017·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·Maturin Tabue-TeguoJean François Dartigues
Jun 8, 2017·Circulation·Frank J WoltersUNKNOWN Heart-Brain Connection Collaborative Research Group

❮ Previous
Next ❯

Citations

Oct 11, 2019·Stroke; a Journal of Cerebral Circulation·Michelle C JohansenRebecca F Gottesman
Dec 18, 2019·Clinical Cardiology·Eiran Z Gorodeski, Ardeshir Z Hashmi
Jul 16, 2020·Der Internist·S M WedegärtnerI Kindermann
Jun 20, 2020·Internal and Emergency Medicine·José Miguel García BruñénUNKNOWN RICA Investigators Group
Jul 31, 2021·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Ronald J EllisRobert K Heaton
Jul 11, 2020·The Journal of Cardiovascular Nursing·Kenneth M FaulknerGail D'Eramo Melkus

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.