Heart failure caused by VGAM: a lesson for diagnosis and treatment from a case and literature review.

The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians
Caterina SpadaLorenzo Iughetti


We describe the case of a neonate with signs of heart failure. Echocardiography showed a structural normal heart shape with left ventricular dysfunction. At 2 months of age, a vein of Galen arteriovenous malformation was diagnosed through a brain magnetic resonance imaging. Embolization therapy was accomplished and a clinical and neurological follow-up was started. This clinical case highlights how important it is considering an intracranial cause in the differential diagnosis of neonatal congestive heart failure (CHF). We performed a narrative minireview of the literature about treatments and outcome of this malformation in association to CHF, to point out how complex the diagnosis of vein of Galen aneurysmal malformation (VGAM) may be and how an early diagnosis is important for its management.


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Oct 17, 2015·Pediatric Annals·Theodore De BerittoMichael Schreiber
Feb 23, 2017·World Journal of Clinical Pediatrics·Surasak PuvabanditsinDavid Sorrentino
Jul 11, 2018·American Journal of Perinatology·Gabriella De RosaMarco Piastra

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