Heart-fatty acid-binding protein as a marker for early detection of acute myocardial infarction and stroke

Molecular Diagnosis : a Journal Devoted to the Understanding of Human Disease Through the Clinical Application of Molecular Biology
Pierre LescuyerJean-Charles Sanchez

Abstract

Heart-fatty acid-binding protein (H-FABP) is a small cytosolic protein involved in intracellular fatty acid transport. This protein, highly concentrated in the heart, is quickly released into plasma after myocardial injury. Results from numerous studies suggest that H-FABP is an excellent marker for the early detection of myocardial damage. H-FABP is also expressed in the brain, although in lower concentrations than in the heart. Recent preliminary studies also investigated the usefulness of H-FABP for the diagnosis of acute and chronic neurological disorders. These potential applications of H-FABP in clinical practice are reviewed in this article, with a strong focus on the early diagnosis of acute myocardial infarction and stroke.

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Citations

Apr 18, 2013·European Archives of Psychiatry and Clinical Neuroscience·Liang-Hao GuoRobert Perneczky
Jun 26, 2009·PLoS Neglected Tropical Diseases·Alexandre HainardJean-Charles Sanchez
Jul 3, 2013·The American Journal of Emergency Medicine·Ali Kemal ErenlerRamazan Amanvermez
Apr 9, 2010·Human & Experimental Toxicology·Turker YardanAhmet Baydin
Apr 19, 2018·Critical Reviews in Clinical Laboratory Sciences·Konstantinos MakrisGeorgios Tsivgoulis
Feb 9, 2010·Expert Review of Neurotherapeutics·Nada El Husseini, Daniel T Laskowitz
Feb 13, 2018·Critical Pathways in Cardiology·Maryam Sotoudeh AnvariArash Jalali
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Jul 1, 2020·Terapevticheskiĭ arkhiv·O V LyangL V Stakhovskaya

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