Heart-fatty acid-binding protein as a marker for early detection of acute myocardial infarction and stroke

Molecular Diagnosis : a Journal Devoted to the Understanding of Human Disease Through the Clinical Application of Molecular Biology
Pierre LescuyerJean-Charles Sanchez


Heart-fatty acid-binding protein (H-FABP) is a small cytosolic protein involved in intracellular fatty acid transport. This protein, highly concentrated in the heart, is quickly released into plasma after myocardial injury. Results from numerous studies suggest that H-FABP is an excellent marker for the early detection of myocardial damage. H-FABP is also expressed in the brain, although in lower concentrations than in the heart. Recent preliminary studies also investigated the usefulness of H-FABP for the diagnosis of acute and chronic neurological disorders. These potential applications of H-FABP in clinical practice are reviewed in this article, with a strong focus on the early diagnosis of acute myocardial infarction and stroke.


Oct 21, 1992·Molecular and Cellular Biochemistry·A H KleineG J Van der Vusse
Jun 1, 1989·Journal of Molecular and Cellular Cardiology·A A KnowltonP Brecher
Sep 1, 1995·Acta Neurologica Scandinavica·K J LamersR A Wevers
Feb 1, 1995·Histochemistry and Cell Biology·W ZschiescheJ F Glatz
Oct 27, 1995·Brain Research. Developmental Brain Research·P A SellnerN E Berman
Apr 1, 1996·Journal of Neurochemistry·S C Myers-PayneF Schroeder
Sep 26, 1996·The New England Journal of Medicine·G HsichM G Harrington
Oct 1, 1996·British Journal of Neurosurgery·S A RossB J Rowlands
Sep 1, 1996·Progress in Lipid Research·J F Glatz, G J van der Vusse
Jun 27, 1997·Clinica Chimica Acta; International Journal of Clinical Chemistry·J IshiiK Kawamura
May 15, 1998·Clinica Chimica Acta; International Journal of Clinical Chemistry·J F GlatzW T Hermens
Jun 26, 1998·Clinica Chimica Acta; International Journal of Clinical Chemistry·K W WodzigW T Hermens
Jun 17, 2000·Biochimica Et Biophysica Acta·J Storch, A E Thumser
Jul 6, 2000·Clinica Chimica Acta; International Journal of Clinical Chemistry·J A de LemosN Rifai
May 16, 2001·Current Opinion in Lipidology·J F Glatz, J Storch
Oct 19, 2001·Journal of Neurology, Neurosurgery, and Psychiatry·J de VriesK J Lamers
Dec 19, 2002·Molecular & Cellular Proteomics : MCP·N Leigh Anderson, Norman G Anderson
Aug 26, 2003·The American Journal of Medicine·Allan Jaffe
Sep 23, 2003·Clinical Chemistry·Mark A ReynoldsKenneth F Buechler
Jan 28, 2004·Circulation Journal : Official Journal of the Japanese Circulation Society·Yoshihiko SeinoUNKNOWN Tokyo Rapid-Test Office Cardiologists (Tokyo-ROC) Study
Mar 19, 2004·QJM : Monthly Journal of the Association of Physicians·H A Alhadi, K A A Fox
Apr 20, 2004·Current Opinion in Neurology·Peter D SchellingerWerner Hacke
May 26, 2004·Zeitschrift für Kardiologie·C P Y ChanR Renneberg
Jun 12, 2004·Current Atherosclerosis Reports·Peter D Schellinger, Steven Warach
Jul 13, 2004·European Heart Journal·Mauro Panteghini
Jul 21, 2004·Journal of the American College of Cardiology·Robert A Kloner, Shereif H Rezkalla

❮ Previous
Next ❯


Apr 18, 2013·European Archives of Psychiatry and Clinical Neuroscience·Liang-Hao GuoRobert Perneczky
Jun 26, 2009·PLoS Neglected Tropical Diseases·Alexandre HainardJean-Charles Sanchez
Jul 3, 2013·The American Journal of Emergency Medicine·Ali Kemal ErenlerRamazan Amanvermez
Apr 9, 2010·Human & Experimental Toxicology·Turker YardanAhmet Baydin
Apr 19, 2018·Critical Reviews in Clinical Laboratory Sciences·Konstantinos MakrisGeorgios Tsivgoulis
Feb 9, 2010·Expert Review of Neurotherapeutics·Nada El Husseini, Daniel T Laskowitz
Feb 13, 2018·Critical Pathways in Cardiology·Maryam Sotoudeh AnvariArash Jalali
Sep 29, 2007·Cytogenetic and Genome Research·I SzczerbalM Switonski
Jul 1, 2020·Terapevticheskiĭ arkhiv·O V LyangL V Stakhovskaya

❮ Previous
Next ❯

Related Concepts

Related Feeds

Acute Stroke

A stroke occurs when blood supply to the brain is interrupted depriving the brain of oxygen and nutrients. This feed focuses cerebrovascular accidents including ischemic and paralytic stroke.


Cardiomyopathy is a disease of the heart muscle, that can lead to muscular or electrical dysfunction of the heart. It is often an irreversible disease that is associated with a poor prognosis. There are different causes and classifications of cardiomyopathies. Here are the latest discoveries pertaining to this disease.