Heart rate and blood pressure variabilities in salt-sensitive hypertension

Hypertension
G PiccirilloV Marigliano

Abstract

In salt-sensitive hypertension, a high sodium intake causes plasma catecholamines to rise and pulmonary baroreceptor plasticity to fall. In salt-sensitive and salt-resistant hypertensive subjects during low and high sodium intakes, we studied autonomic nervous system activity by power spectral analysis of heart rate and arterial pressure variabilities and baroreceptor sensitivity. In all subjects, high sodium intake significantly enhanced the low-frequency power of heart rate and arterial pressures at rest and after sympathetic stress. It also increased heart rate and arterial pressure variabilities. During high sodium intake, salt-sensitive hypertensive subjects had significantly higher low-frequency powers of systolic arterial pressure (7.5 mm Hg2, P < .05) and of heart rate at rest (59.2 +/- 2.4 normalized units [NU], P < .001) than salt-resistant subjects (6.6 +/- 0.3 mm Hg2, 55.0 +/- 3.2 NU) and normotensive control subjects (5.1 +/- 0.5 mm Hg2, 41.6 +/- 2.9 NU). In salt-sensitive subjects, low sodium intake significantly reduced low-frequency normalized units (P < .001) and the ratio of low- to high-power frequency (P < .001). High-sodium intake significantly increased baroreflex sensitivity in control subjects (from 10.0...Continue Reading

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Citations

Dec 13, 2000·The American Journal of Cardiology·G PiccirilloM Cacciafesta
Sep 18, 2004·Archives of Gerontology and Geriatrics·G PiccirilloV Marigliano
Sep 14, 2001·Journal of the American Geriatrics Society·G PiccirilloM Cacciafesta
Jun 15, 2006·Journal of the American College of Nutrition·Michael H Alderman
Mar 11, 2005·Diabetes/metabolism Research and Reviews·Arye Lev-Ran, Massimo Porta
Nov 5, 2011·The Journal of Clinical Hypertension·May E MontasserBraxton D Mitchell
May 11, 1999·The Journal of Laboratory and Clinical Medicine·G PiccirilloV Marigliano
Mar 1, 2000·The Journal of Laboratory and Clinical Medicine·G PiccirilloV Marigliano
Jul 18, 2006·Autonomic Neuroscience : Basic & Clinical·Vera FarahMariana Morris
Jul 30, 2005·International Journal of Cardiology·Gianfranco PiccirilloDamiano Magrì
Mar 3, 2015·Heart Failure Reviews·Marcelo Perim BaldoJosé Geraldo Mill
May 29, 2010·American Journal of Hypertension·Jennifer N NjorogeKim Sutton-Tyrrell
Apr 11, 2018·American Journal of Physiology. Renal Physiology·Takahiro YamauchiTakao Masaki
Jan 28, 2006·Clinical Chemistry·Hironobu SanadaRobin A Felder
Mar 1, 2005·American Journal of Physiology. Heart and Circulatory Physiology·Michael D Hendel, John P Collister
Feb 26, 2004·Clinical Science·Gianfranco PiccirilloVincenzo Marigliano
Jul 27, 2021·Advanced Healthcare Materials·Junnan TangJinying Zhang

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