Heart rate and blood pressure variability: implications for psychiatric research

Neuropsychobiology
Vikram Kumar Yeragani

Abstract

Symptoms of anxiety suggest autonomic dysfunction and most of the psychotropic agents used to treat anxiety and affective disorders have strong autonomic effects. This article describes the utility and importance of analysis of heart rate and blood pressure time series to study cardiac autonomic function in psychiatric research. The variability of heart rate between 0.15 and 0.5 Hz is related to respiratory sinus arrhythmia, and is modulated by cholinergic activity in both supine and standing postures, while the variability between 0.04 and 0.15 Hz is dually influenced by cholinergic and adrenergic mechanisms which can be used as a relative measure of sympathetic activity in standing posture. Analysis of beat-to-beat control of heart rate and blood pressure gives important information about cardiac sympathetic and parasympathetic interaction, which could be used to study the possible link between anxiety and depressive disorders and increased cardiovascular morbidity.

Citations

Jul 12, 2002·Depression and Anxiety·K SrinivasanVikram K Yeragani
Jan 31, 2004·Progress in Neuro-psychopharmacology & Biological Psychiatry·Jong-Hoon KimYong Sik Kim
Feb 28, 2003·Psychiatry Research·Vikram Kumar Yeragani, K A Radhakrishna Rao
Oct 12, 2001·Autonomic Neuroscience : Basic & Clinical·R K RadhakrishnaV K Yeragani
Jul 28, 2001·Autonomic Neuroscience : Basic & Clinical·R K Rao, V K Yeragani
Jun 16, 2011·Psychological Medicine·R A BryantA C McFarlane
Sep 20, 2007·Journal of Pediatric Orthopedics·Raymond W LiuAllison Gilmore
Dec 5, 2009·The American Journal of Medicine·Azad A KabirGerald S Berenson
May 2, 2002·Biological Psychiatry·Vikram Kumar YeraganiK Srinivasan
Jul 1, 1997·Cardiovascular Research·V K YeraganiG Igel
Jul 23, 2020·Journal of Pediatric Orthopedics. Part B·Brandon J BarnesChad E Aarons

❮ Previous
Next ❯

Related Concepts

Related Feeds

Arrhythmia

Arrhythmias are abnormalities in heart rhythms, which can be either too fast or too slow. They can result from abnormalities of the initiation of an impulse or impulse conduction or a combination of both. Here is the latest research on arrhythmias.

Atrial Fibrillation

Atrial fibrillation is a common arrhythmia that is associated with substantial morbidity and mortality, particularly due to stroke and thromboembolism. Here is the latest research.