Heart rate and cardiovascular disease: an alternative to Beta blockers.

Cardiology Research and Practice
Michael LiangGerard Devlin

Abstract

Ivabradine, an I(f) inhibitor, acts primarily on the sinoatrial node and is used to reduce the heart rate with minimal effect on myocardial contractility, blood pressure, and intracardiac conduction. Heart rate reduction is an important aspect of care in patients with chronic stable angina and heart failure. Many patients with coronary artery disease have coexisting asthma or chronic obstructive airway disease, and most of them are unable to tolerate beta blockers. Ivabradine may thus be a useful medicine in therapeutic heart rate management especially in patients who are intolerant of beta-blockers.

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Feb 5, 2016·European Journal of Clinical Investigation·Aref NajafiJolanda van der Velden
Jul 7, 2012·Clinical Drug Investigation·Laurian VlaseSorin E Leucuta
Mar 15, 2018·American Journal of Cardiovascular Drugs : Drugs, Devices, and Other Interventions·Hitesh ShuklaAbdullah Sabyah
Jan 25, 2011·Expert Opinion on Pharmacotherapy·Graziano Riccioni

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