Heart rate turbulence for prediction of heart transplantation and mortality in chronic heart failure.

Annals of Noninvasive Electrocardiology : the Official Journal of the International Society for Holter and Noninvasive Electrocardiology, Inc
Beata SredniawaZbigniew Kalarus

Abstract

Previous studies have shown conflicting results about the value of heart rate turbulence (HRT) for risk stratification of patients (pts) with chronic heart failure (CHF). We prospectively evaluated the relation between HRT and progression toward end-stage heart failure or all-cause mortality in patients with CHF. HRT was assessed from 24-hour Holter recordings in 110 pts with CHF (54 in NYHA class II, 56 in class III-IV; left ventricular ejection fraction (LVEF) 30%+/- 10%) on optimal pharmacotherapy and quantified as turbulence onset (TO,%), turbulence slope (TS, ms/RR interval), and turbulence timing (beginning of RR sequence for calculation of TS, TT). TO > or = 0%, TS < or = 2.5 ms/RR, and TT >10 were considered abnormal. End point was development of end-stage CHF requiring heart transplantation (OHT) or all-cause mortality. During a follow-up of 5.8 +/- 1.3 years, 24 pts died and 10 required OHT. TO, TS, TT, and both (TO and TS) were abnormal in 35%, 50%, 30%, and 25% of all patients, respectively. Patients with at least one relatively preserved HRT parameter (TO, TS, or TT) (n = 98) had 5-year event-free rate of 83% compared to 33% of those in whom all three parameters were abnormal (n = 12). In multivariate Cox regressio...Continue Reading

References

Jan 1, 1989·The American Journal of Cardiology·F RomeoA Reale
Jan 1, 1994·Annual Review of Medicine·T S Rector, J N Cohn
Sep 1, 1996·Journal of Cardiac Failure·P PonikowskiA J Coats
Sep 27, 2000·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·R MrowkaA Patzak
May 4, 2001·The American Journal of Medicine·E J Eichhorn
Jan 17, 2002·The New England Journal of Medicine·E A RoseUNKNOWN Randomized Evaluation of Mechanical Assistance for the Treatment of Congestive Heart Failure (REMATCH) Study Group
Oct 17, 2002·Circulation Journal : Official Journal of the Japanese Circulation Society·Jiro KoyamaKunio Shirato
Nov 1, 2002·The New England Journal of Medicine·Daniel LevyRamachandran S Vasan
Nov 26, 2002·Journal of the American College of Cardiology·Mark T KearneyJames Nolan
Dec 11, 2002·Circulation·Donald M Lloyd-JonesUNKNOWN Framingham Heart Study
Jul 8, 2003·Circulation Journal : Official Journal of the Japanese Circulation Society·Tatsuya KawasakiHiroki Sugihara
Aug 27, 2003·Circulation·Petra BarthelGeorg Schmidt
Jan 22, 2005·The New England Journal of Medicine·Gust H BardyUNKNOWN Sudden Cardiac Death in Heart Failure Trial (SCD-HeFT) Investigators
Mar 9, 2005·The New England Journal of Medicine·John G F ClelandUNKNOWN Cardiac Resynchronization-Heart Failure (CARE-HF) Study Investigators
Feb 14, 2006·European Journal of Heart Failure·Roger K G MooreMark T Kearney
Jul 14, 2006·Journal of Cardiovascular Electrophysiology·Mari A Watanabe
Sep 12, 2006·The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation·Mandeep R MehraMark Barr
Dec 6, 2006·The American Journal of Cardiology·Iwona CygankiewiczAntonio Bayes de Luna
Sep 4, 2007·BMC Public Health·Raffaele Antonelli-IncalziCarlo A Perucci
Aug 5, 2008·Heart Rhythm : the Official Journal of the Heart Rhythm Society·Iwona CygankiewiczUNKNOWN Muerte Subita en Insuficiencia Cardiaca Investigators
Jan 22, 2009·European Heart Journal·Heikki V HuikuriUNKNOWN Cardiac Arrhythmias and Risk Stratification after Acute Myocardial Infarction study group
Mar 11, 2009·Pacing and Clinical Electrophysiology : PACE·Beata SredniawaZbigniew Kalarus
Mar 31, 2009·The American Journal of Cardiology·Iwona CygankiewiczUNKNOWN MUSIC Investigators

❮ Previous
Next ❯

Citations

Aug 29, 2009·Circulation Journal : Official Journal of the Japanese Circulation Society·Jun-Gol SongJin Woo Shin
Nov 13, 2013·Progress in Cardiovascular Diseases·Iwona Cygankiewicz
Jul 24, 2012·Annals of Noninvasive Electrocardiology : the Official Journal of the International Society for Holter and Noninvasive Electrocardiology, Inc·Sylwia CebulaZbigniew Kalarus
Jun 7, 2014·Annals of Noninvasive Electrocardiology : the Official Journal of the International Society for Holter and Noninvasive Electrocardiology, Inc·Piotr BieniasPiotr Pruszczyk
Jun 3, 2020·Physiological Measurement·Valeria BlesiusAndreas Dominik

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Heart Rhythm : the Official Journal of the Heart Rhythm Society
Iwona CygankiewiczMuerte Subita en Insuficiencia Cardiaca Investigators
Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology
Gaetano PinnacchioFilippo Crea
© 2021 Meta ULC. All rights reserved