PMID: 8945053Nov 1, 1996Paper

Heart rate variability and major arrhythmic events in patients with idiopathic dilated cardiomyopathy

Pacing and Clinical Electrophysiology : PACE
J HoffmannB Maisch

Abstract

This prospective study of 71 patients with idiopathic dilated cardiomyopathy (IDC) and preserved sinus rhythm was designed to evaluate the relation between heart rate variability (HRV) and subsequent major arrhythmic events. Standard time- and frequency-domain HRV parameters were obtained from analysis of 24-hour Holter ECG recordings. During a mean follow-up of 15 +/- 5 months, major arrhythmic events including sustained ventricular tachycardia, ventricular fibrillation, and sudden cardiac death occurred in 10 of the 71 study patients (14%). Neither time- nor frequency-domain indices of HRV differed significantly between patients with and patients without subsequent major arrhythmic events. However, there was a trend toward a lower standard deviation of the average normal RR interval for all 5-minute segments of the 24-hour recording (68 +/- 17 ms vs 80 +/- 31 ms; P = 0.06) in patients with major arrhythmic events. In addition, the percentage of adjacent normal RR intervals differing > 50 ms over the recording period tended to be lower in patients with major arrhythmic events (6% +/- 3% vs 9% +/- 6%; P = 0.08). Our results indicate a tendency toward attenuated parasympathetic activity in IDC patients with subsequent major arrh...Continue Reading

References

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Citations

Dec 16, 2006·Annals of Biomedical Engineering·Mathias BaumertDerek Abbott
Dec 7, 2002·International Journal of Cardiology·Maciej KarczWitold Ruzyłło
Jan 15, 2002·Journal of the American College of Cardiology·Hidetsuna KitamuraMitsuhiro Yokoyama
Jan 14, 2012·Circulation Journal : Official Journal of the Japanese Circulation Society·UNKNOWN JCS Joint Working Group
Jan 23, 2015·Indian Pacing and Electrophysiology Journal·Sp Abhilash, Narayanan Namboodiri
Feb 28, 2006·Heart Rhythm : the Official Journal of the Heart Rhythm Society·James D AllredRaymond E Ideker
Jan 22, 2014·Journal of the American College of Cardiology·Jeffrey J GoldbergerAlan H Kadish
Jun 19, 2016·Computers in Biology and Medicine·Yoon Jae KimSungwan Kim
Mar 12, 1999·Annual Review of Medicine·P K Stein, R E Kleiger
Feb 3, 2005·Pacing and Clinical Electrophysiology : PACE·Wolfram GrimmBernhard Maisch
Nov 24, 1998·Pacing and Clinical Electrophysiology : PACE·V MenzB Maisch
Oct 12, 1999·Journal of Cardiovascular Electrophysiology·S ChallapalliJ J Goldberger

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