Heart rate variability as an index of cue reactivity in alcoholics

Biological Psychiatry
I RajanN Janakiramaiah

Abstract

Autonomic responses follow exposure to conditioned stimuli such as contextual factors associated with alcohol ingestion. Heart rate variability is under autonomic control and may be a measure of such response. Twenty alcoholics and 23 matched social drinkers (all male) were exposed to a neutral cue and then an alcohol cue in identical settings, during which the electrocardiogram of these subjects was recorded. Time and frequency domain parameters of heart rate variability (HRV) were computed by a blind rater. Coefficient of variation of R-R intervals and absolute powers of HRV spectrum (in frequency bands 0.05-0.15 Hz and 0.01-0.05 Hz) following alcohol cue were significantly higher in alcoholics than social drinkers. The mean heart rate (MHR) failed to reflect this difference. HRV paradigm appears more sensitive than MHR to measure cue reactivity.

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Citations

Dec 17, 2009·International Archives of Occupational and Environmental Health·Mikio TakadaMichihiro Kamijima
Sep 12, 2006·Addiction Biology·Richard L BellWilliam J McBride
Feb 13, 2010·Addiction Biology·John C CrabbeCindy L Ehlers
Jul 5, 2013·Indian Journal of Psychiatry·Suhas GaneshaBangalore N Gangadhar
Mar 23, 2011·Addictive Behaviors·Joel ErblichRichard P Sloan
Aug 21, 2008·Pharmacology, Biochemistry, and Behavior·Richard L BellJames M Murphy
Aug 11, 2006·Alcoholism, Clinical and Experimental Research·Esther van den WildenbergReinout W Wiers
Jul 17, 2015·Applied Psychophysiology and Biofeedback·Jong-Min Woo, Tae-Suk Kim

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