Heart rate variability in middle-aged men with new-onset hypertension.

Annals of Noninvasive Electrocardiology : the Official Journal of the International Society for Holter and Noninvasive Electrocardiology, Inc
Purushothaman PavithranHanumanthappa Nandeesha

Abstract

It has been well established that hypertension is associated with autonomic dysregulation. Studies investigating HRV have established that hypertension is characterized by sympathetic overactivity and or attenuation of parasympathetic modulation of the heart. We examined short-term heart rate variability (HRV) as well as conventional indices of cardiovascular autonomic function including heart rate variation during deep breathing (HRVdb), 30: 15 ratio, pressor response to quiet standing and isometric handgrip in 35 male subjects (39 +/- 7 year, mean +/- SD) with new-onset hypertension (resting BP 155 +/- 17/101 +/- 8 mm Hg) and 17 age-matched normotensive men (resting BP: 111 +/- 7/71 +/- 5 mmHg). HRVdb was significantly lower in hypertensives (21 +/- 8) compared to normotensives (mean age 36 +/- 7, P = 0.03). Differences in mean RR were insignificant, logarithm of high-frequency (HF) spectral power of RR intervals was significantly lower in hypertensives compared to normotensives in the supine position (P = 0.02). Our data suggest that new-onset hypertension is characterized by diminished short-term HRV, possibly due to an increase in cardiovascular sympathovagal balance.

References

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Citations

Feb 11, 2010·Cardiology in the Young·Klaus SchmidMichael Mueck-Weymann
Oct 1, 2011·Hypertension Research : Official Journal of the Japanese Society of Hypertension·Izabela C CozzaHugo C D Souza
Nov 25, 2014·Journal of the American Society of Hypertension : JASH·Marijana TadicVera Celic
Nov 15, 2011·Amyloid : the International Journal of Experimental and Clinical Investigation : the Official Journal of the International Society of Amyloidosis·Udi NussinovitchAvi Livneh
Dec 12, 2012·Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia·Chien-Fu ChenChiou-Lian Lai
Jan 20, 2011·Pediatric Pulmonology·Ka-Li KwokYu-Ming Fu
May 27, 2016·Annals of Noninvasive Electrocardiology : the Official Journal of the International Society for Holter and Noninvasive Electrocardiology, Inc·Anne Kastelianne França da SilvaLuiz Carlos Marques Vanderlei
Sep 17, 2011·Stroke; a Journal of Cerebral Circulation·Zeynep BiniciAhmad Sajadieh
Aug 20, 2019·Journal of Investigative Medicine : the Official Publication of the American Federation for Clinical Research·Keren PolitiUdi Nussinovitch
Jul 4, 2020·International Journal of Psychophysiology : Official Journal of the International Organization of Psychophysiology·Jeongok G LoganBrian H Annex
Feb 3, 2021·Complementary Therapies in Clinical Practice·Katherine Ka-Yin Yau, Alice Yuen Loke

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