Heart retransplantation for pediatric primary allograft failure

Transplantation Proceedings
J M LuoShoei-Shen Wang

Abstract

Heart transplantation is indicated for children with end-stage heart failure or complex inoperable congenital defects. When the transplanted heart fails, retransplantation is suggested and herein we have presented the prognosis of these pediatric cases. From March 1987 to March 2011, we performed 404 heart transplantations including 45 pediatric patients, 6 (13.3%) of whom experienced graft failure requiring retransplantation. Only four of the six patients (66.7%) had a chance for retransplantation. Six of 45 pediatric heart transplant patients (13.3%) experienced graft failure requiring retransplantation. Four of them (66.7%) underwent retransplantation. Only one of the four died due to severe postoperative sepsis with acute respiratory distress. The other three patients recovered well and remain alive with no neurological sequelae; all are in New York Heart Association functional classification I at present. Pediatric post-heart graft failure require expectations retransplantation, which shows a good prognosis.

References

Jul 21, 2007·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·M R JohnsonS A Webber
Aug 1, 2007·Pediatric Transplantation·Marc E RichmondJacqueline M Lamour
Apr 26, 2008·Pediatric Transplantation·William T Mahle
Aug 30, 2011·The Annals of Thoracic Surgery·Alexander IribarneMark J Russo

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Citations

Apr 2, 2014·Mayo Clinic Proceedings·Jeffrey A RobinsonJonathan N Johnson

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