Heart transplantation from donation after circulatory determined death

Annals of Cardiothoracic Surgery
Aravinda PageStephen Large

Abstract

Fifty years since the first successful human heart transplant from a non-heart beating donor, this concept of heart transplantation from donation after circulatory determined death (DCD) promises to be one of the most exciting developments in heart transplantation. Heart transplantation has established itself as the best therapeutic option for patients with end-stage heart failure, with the opportunity to provide these patients with a near-normal quality of life. However, this treatment is severely limited by the availability of suitable donor hearts. In recent times, heart transplantation has been limited to using donor hearts from donors following brain stem death. The use of donor hearts from DCD had been thought to be associated with high risk and poor outcomes until recent developments in organ perfusion and retrieval techniques have shown that this valuable resource may provide an answer to the global shortage of suitable donor hearts. With established DCD heart transplant programmes reporting encouraging results, this technique has been shown to be comparable to the current gold standard of donation after brain death (DBD) heart transplantation.

Citations

Apr 26, 2019·Heart Failure Reviews·Sanjeet Singh Avtaar SinghNawwar Al-Attar
Nov 28, 2019·American Journal of Physiology. Heart and Circulatory Physiology·Bryan GellnerMitesh V Badiwala
Sep 3, 2019·The Journal of International Medical Research·Vasileios Zochios, Aristotle D Protopapas
Oct 2, 2019·Nature Reviews. Cardiology·Jonathan M KalmanDong Zhao
Mar 16, 2019·Frontiers in Immunology·Judith E van ZandenMarc A Seelen
Jun 27, 2019·The International Journal of Artificial Organs·Carolin OlbertzAchim Koch
Apr 19, 2019·Circulation. Heart Failure·Petra NiederbergerSarah L Longnus
Oct 12, 2019·Advanced Healthcare Materials·Marleen KristenMiguel Castilho
Jan 5, 2019·Der Chirurg; Zeitschrift für alle Gebiete der operativen Medizen·S V Rojas, A Haverich
Dec 29, 2020·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Christian Østergaard MariagerChristoffer Laustsen
Apr 20, 2020·The Journal of Thoracic and Cardiovascular Surgery·Jason J HanPavan Atluri
Dec 15, 2020·Interactive Cardiovascular and Thoracic Surgery·Bhuvaneswari KrishnamoorthyRajamiyer Venkateswaran
Nov 10, 2020·The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation·Lu WangJohn H Dark
May 13, 2019·Translational Research : the Journal of Laboratory and Clinical Medicine·Matthew AlonzoBinata Joddar
Jul 8, 2019·Current Opinion in Biotechnology·Reinier J de VriesKorkut Uygun
May 2, 2020·The Journal of Thoracic and Cardiovascular Surgery·Henry AcerosNicolas Noiseux
Mar 31, 2021·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Katrien VandendriesscheFilip Rega
Jul 14, 2021·The Hastings Center Report·Franklin G MillerRobert D Truog
Mar 30, 2019·Journal of the American College of Cardiology·Francis D Pagani
Aug 19, 2021·Current Problems in Cardiology·Ahmed Al-AdhamiNawwar Al-Attar
Sep 16, 2021·Netherlands Heart Journal : Monthly Journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation·N de JongeK Caliskan

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