PMID: 8957378Dec 1, 1996Paper

Heart transplantation in patients 70 years of age and older: initial experience

The Annals of Thoracic Surgery
C BlancheA Trento

Abstract

Heart transplantation has become a highly successful therapeutic option for patients with end-stage cardiomyopathy. Consequently, the criteria for patient selection, particularly regarding recipients' upper age limits, have been expanded, with an increasing number of people older than 60 years of age now undergoing transplantation. A retrospective analysis of 6 patients 70 years of age and older who underwent heart transplantation was done; their clinical courses and outcomes were compared with those of younger patients, with a special emphasis on their posttransplantation quality of life. All 6 patients are alive and clinically well at a mean follow-up of 12 months. No age-related complications have been observed, and their quality of life is excellent. There has been a very low incidence of rejection, as well as few episodes of rejection. Heart transplantation in selected people 70 years of age and older can be performed successfully with a morbidity comparable to that seen in younger patients and excellent short-term survival. This initial experience is encouraging, but further studies and long-term follow-up are needed to validate the more routine application of this therapy.

References

Feb 1, 1988·The Annals of Thoracic Surgery·O H FrazierD A Cooley
Nov 1, 1994·The Annals of Thoracic Surgery·C BlancheJ Matloff
Aug 1, 1994·The Annals of Thoracic Surgery·T P TsaiS S Khan
Aug 15, 2001·The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation·J D HosenpudR J Novick

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Citations

Dec 31, 2003·Transplantation Proceedings·A Gambino
Dec 12, 2003·The Annals of Thoracic Surgery·Jeffrey A MorganNiloo M Edwards
Sep 29, 1999·Transplantation Proceedings·M G Crespo-LeiroA Castro-Beiras
Jun 19, 2001·The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation·E A BocchiUNKNOWN First Guideline Group for Heart Transplantation of the Brazilian Society of Cardiology
Aug 19, 1999·The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation·A M BorkonS K Rowe
May 5, 2012·The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation·Daniel J GoldsteinDavid D'Alessandro
Feb 25, 2003·Critical Care Nursing Clinics of North America·Linda S BaasLynne E Wagoner
Dec 17, 2011·Transplantation Proceedings·D DaneshvarA Trento
Mar 10, 2001·The Journal of Thoracic and Cardiovascular Surgery·C BlancheA Trento
Sep 16, 2004·The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation·Maninder BediDennis M McNamara
Jun 3, 2004·The Journal of Thoracic and Cardiovascular Surgery·Jeffrey A MorganNiloo M Edwards
Feb 21, 2002·AACN Clinical Issues·Linda S BaasLynne E Wagoner
Dec 1, 1999·AACN Clinical Issues·T K RourkeL Ohler
Aug 22, 2000·Current Opinion in Cardiology·M M KoernerG Torre-Amione
Aug 30, 2000·Current Opinion in Cardiology·G C Fonarow
Jun 18, 2003·Journal of Cardiac Surgery·Alberto JuffeMarisa Crespo
Jan 18, 2012·The Journal of Thoracic and Cardiovascular Surgery·Arman KilicJohn V Conte
Aug 5, 2000·Clinics in Geriatric Medicine·M S Slaughter, H B Ward

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