Heart valve disease in elderly

World Journal of Cardiology
Carlo Rostagno

Abstract

The incidence of heart valve disease increases significantly with age. Degenerative abnormalities associated with severe aortic stenosis and mitral and tricuspid regurgitation are found in not less than 10% of the population aged ≥ 75 years. Surgical treatment has been considered for years to be the treatment of choice. However, it was not uncommonly associated with high perioperative morbidity and mortality due to frequent comorbidities and overall frailty conditions of these patients. Conventional risk scores such as Society of Thoracic Surgeons and European System for Cardiac Operative Risk Evaluation may underestimate the risk of surgery in elderly patients, leading to inappropriate surgical indication. On the other hand, at least 30% of patients with severe conditions are left untreated due to prohibitive surgical risk. Interventional procedures, which are in continuous development, may be actually considered for high risk patients and, as recent results suggest, also for intermediate risk patients.

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Sep 6, 2019·Herz·J VogelhuberG Nickenig
Sep 11, 2020·Open Heart·Anda BulargaNick Cruden
Jun 12, 2020·Heart Failure Reviews·Filippos TriposkiadisDimitrios Farmakis
Oct 17, 2020·American Journal of Physiology. Heart and Circulatory Physiology·Stamatia PagoulatouDionysios Adamopoulos
Apr 15, 2021·Monaldi Archives for Chest Disease = Archivio Monaldi Per Le Malattie Del Torace·Chiara PenatiOreste Carlo Febo
Jun 5, 2021·Journal of Theoretical Biology·Andrei A Domogo, Johnny T Ottesen
Aug 26, 2021·Cell Reports·Liam A RidgeSarah Ivins

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Methods Mentioned

BETA
coronary artery bypass

Software Mentioned

Trialign

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