PMID: 9647070Jul 1, 1998Paper

HeartMate left ventricular assist device as bridge to heart transplantation

The Annals of Thoracic Surgery
B KoulU J Lönn

Abstract

Because of the limited supply of donor hearts, prospective recipients continue to die while on the waiting list for heart transplantation. Use of long-term mechanical circulatory support devices as a bridge to transplantation may reduce this mortality. However, with the present state of technology, continued clinical evaluation of the various long-term, mechanical circulatory support devices available is mandatory. Sixteen patients were bridged with the HeartMate left ventricular assist device (LVAD) to heart transplantation for New York Heart Association functional class IV cardiac failure. Twelve pneumatic and six electric devices were used. The mean cardiac index and the mean pulmonary vascular resistance of the patient cohort were 1.71 x min(-1) x m(-2) and 3.1 Wood units, respectively. The mean LVAD support time per transplanted patient was 237 days, with a cumulative LVAD support time of about 7.2 years. Bleeding was the main operative and postoperative complication. Two patients suffered from neurologic complications and there were two major incidents of device malfunction. Twelve patients (75%) now have received a transplant, 3 (19%) are awaiting a transplant, and in 1 patient (6%), the device was explanted after sponta...Continue Reading

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Citations

Jan 5, 2002·The Japanese Journal of Thoracic and Cardiovascular Surgery : Official Publication of the Japanese Association for Thoracic Surgery = Nihon Kyōbu Geka Gakkai Zasshi·K NishimuraM Komeda
Aug 31, 2000·The Japanese Journal of Thoracic and Cardiovascular Surgery : Official Publication of the Japanese Association for Thoracic Surgery = Nihon Kyōbu Geka Gakkai Zasshi·S KyoR Omoto
Jun 19, 2007·Journal of Artificial Organs : the Official Journal of the Japanese Society for Artificial Organs·Yusuke AbeKou Imachi
Mar 5, 2011·Journal of Artificial Organs : the Official Journal of the Japanese Society for Artificial Organs·Wei ShiYusuke Abe
Aug 29, 2012·Journal of Artificial Organs : the Official Journal of the Japanese Society for Artificial Organs·Yusuke AbeKou Imachi
Oct 18, 2001·The Annals of Thoracic Surgery·C E ThomasR J Schwartzman
Dec 10, 1999·The Annals of Thoracic Surgery·L ArusogluA El-Banayosy
Mar 29, 2000·The Annals of Thoracic Surgery·U W KjellmanL Wiklund
Jul 25, 2003·The Journal of Thoracic and Cardiovascular Surgery·Darius G NabaviE Bernd Ringelstein
Nov 15, 2002·The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation·Thomas R Cimato, Mariell Jessup
Mar 14, 2003·The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation·M C D DalbyM H Yacoub
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