PMID: 41438May 1, 1979

Heat-selected mutants of pigeon pox virus

Acta Virologica
H H TantawiM O Shony

Abstract

Two mutants of pigeon pox virus were derived from virus isolated from naturally infected pigeons. One (S 39) was obtained by cultivation of the original virus in chick embryo chorioallantoic membranes at 39 degrees C, and the second (S m) by heating the original virus at 56 degrees C for 30 min. The mutants were less pathogenic to pigeons than the original virus. The original virus and the mutant S 39, but not the mutant S m produced plaques in primary chick embryo cell cultures. Pigeons inoculated with the mutants were resistant to challenge with the field virus.

Related Concepts

Pathogenicity
Pathogenic Organism
Cell Culture Techniques
Culture Techniques
Fowlpox virus
Senile Plaques
Chick Embryo
Mutant
Columbidae
Columba livia

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