PMID: 11932006Apr 5, 2002Paper

Heat shock protein Hsp70 expression and DNA damage in Baikalian sponges exposed to model pollutants and wastewater from Baikalsk Pulp and Paper Plant

Aquatic Toxicology
Sofia M EfremovaHeinz C Schröder

Abstract

Lake Baikal, a unique habitat for a great number of endemic species, is the largest freshwater reservoir in the world which is still largely unaffected by anthropogenic pollution, except for some shore regions with industrial activity. The expressions of a biomarker of exposure (heat shock protein Hsp70) and a biomarker of effect (DNA single-strand breaks) were measured for the first time in endemic Baikalian sponge species (Baikalospongia intermedia, Lubomirskia fusifera, and Lubomirskia abietina). Tissue cubes of B. intermedia and dissociated cells of L. fusifera and L. abietina reacted to temperature stress (10-16 degrees C above ambient temperature) with a time-dependent increase in expression of Hsp70. In B. intermedia, the effects of model pollutants (lead, copper, and zinc, and the organochlorines tetrachloroguaiacol, TCG, and pentachlorophenol, PCP) and of the wastewater from the final refinement and aeration reservoirs of the Baikalsk Pulp and Paper Plant (BPPP), located at the shore of the southern basin of Lake Baikal, on the expression of Hsp70 and the extent of DNA damage were investigated. It was found that lead and zinc but not copper cause a strong induction of Hsp70 in this sponge, while the frequency of DNA si...Continue Reading

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Citations

Jan 12, 2011·Marine Biotechnology·Lubov I ChernogorAlexander V Ereskovsky
Nov 17, 2009·In Vitro Cellular & Developmental Biology. Animal·Marina PozzoliniMarco Giovine
Aug 20, 2014·BioMed Research International·Khalid MahmoodJamshaid Hussain
Jun 8, 2007·Comparative Biochemistry and Physiology. Part B, Biochemistry & Molecular Biology·Qiang GaoYaqing Chang
Jan 25, 2007·Journal of Biochemistry and Molecular Biology·Eun Kyung Cho, Song-Ja Bae
Jan 25, 2007·Journal of Biochemistry and Molecular Biology·Hiroaki NagaiHidenori Ichijo
Jul 31, 2008·Prikladnaia biokhimiia i mikrobiologiia·M a TimofeevA V Kolesnichenko
Jul 12, 2017·Environmental Toxicology and Chemistry·Rachael U AkpiriNikolas J Hodges
Nov 28, 2019·International Journal of Environmental Health Research·Elif Kaval OğuzAhmet R Oğuz
Aug 6, 2021·Environmental Science and Pollution Research International·Lucia De MarchiFabio Bulleri

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