Heat shock protein synthesis and trehalose accumulation are not required for induced thermotolerance in depressed Saccharomyces cerevisiae

Biochemical and Biophysical Research Communications
C Gross, K Watson

Abstract

Intrinsic and heat shock induced thermotolerance of Saccharomyces cerevisiae was investigated in cells grown on glucose and acetate supplemented media. Heat shocked cells (37 degrees C/30 min), in either medium, exhibited induced synthesis of heat shock proteins (hsp) and trehalose. In all cases, with the notable exception of repressed cells of a relatively thermosensitive strain, heat shock acquisition of thermotolerance also occurred in the absence of protein synthesis and coincident decrease in trehalose accumulation. Results indicted that the marked increase in thermotolerance exhibited by non-fermenting (acetate) cells compared with fermenting (glucose) cells was not closely correlated with levels of hsp or trehalose. It was concluded that mechanisms for intrinsic and induced thermotolerance appear to be different and that growth on acetate endows cells with a biochemical predisposition, other than hsp or trehalose, that confers intrinsic tolerance, a factor which may be subject to heat induced modification.

Citations

Jul 15, 2011·Micron : the International Research and Review Journal for Microscopy·Po-Lin ChiuThomas Walz
Jan 31, 2007·Comparative Biochemistry and Physiology. Part B, Biochemistry & Molecular Biology·K Ingemar Jönsson, Ralph O Schill
May 19, 2010·Aging Cell·Yoko HondaShuji Honda
Sep 22, 2006·The Biochemical Journal·Jan Dijksterhuis, Ronald P de Vries
Jan 1, 1997·Canadian Journal of Microbiology·T M Swan, K Watson
Jan 20, 2004·The Journal of Biological Chemistry·Christopher T WagnerJerome Connor
Sep 30, 2000·Applied and Environmental Microbiology·P LuceroR Lagunas
May 17, 2007·The New Phytologist·Aurora OcónNatalia Requena
Dec 6, 2019·Microbiology and Molecular Biology Reviews : MMBR·Tim J H BaltussenWillem J G Melchers
Jun 13, 2012·Microbiology and Molecular Biology Reviews : MMBR·Jacob VergheseKevin A Morano
Apr 26, 2011·Applied and Environmental Microbiology·Ana Lúcia CarvalhoHelena Santos
May 3, 2015·The Journal of Biological Chemistry·Marjorie PetitjeanJean-Luc Parrou
Nov 27, 1998·Trends in Biotechnology·M A Singer, S Lindquist

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