PMID: 8990297Jan 1, 1997Paper

Heat shock regulation of sigmaS turnover: a role for DnaK and relationship between stress responses mediated by sigmaS and sigma32 in Escherichia coli

Journal of Bacteriology
A MufflerR Hengge-Aronis

Abstract

The cellular level of the rpoS-encoded sigmaS subunit of RNA polymerase increases in response to various stress situations that include starvation, high osmolarity, and shift to acid pH, and these different stress signals differentially affect rpoS translation and/or sigmaS stability. Here we demonstrate that sigmaS is also induced by heat shock and that this induction is exclusively due to an interference with sigmaS turnover. Some sigmaS-dependent genes exhibit similar heat shock induction, whereas others are not induced probably because they need additional regulatory factors that might not be present under conditions of heat shock or exponential growth. Despite its induction, sigmaS does not seem to contribute to heat adaptation but may induce cross-protection against different stresses. While sigmaS is not involved in the regulation of the heat shock sigma factor sigma32, the heat shock protein DnaK has a positive role in the posttranscriptional control of sigmaS. The present evidence suggests that DnaK is involved in the transduction of two of the signals that result in reduced sigmaS turnover, i.e., heat shock and carbon starvation. Heat shock induction of sigmaS also clearly indicates that a cessation of growth or even ...Continue Reading

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Citations

Dec 14, 1999·Molecular Microbiology·A A Bianchi, F Baneyx
Apr 16, 2003·Critical Reviews in Biotechnology·Ashish ParadkarDiane Stassi
Jan 4, 2007·Current Microbiology·Yi-He GeYu-Quan Xu
Dec 20, 2011·Nucleic Acids Research·Kathrin S FröhlichJörg Vogel
Oct 4, 2012·MBio·Kyle A Zingaro, Eleftherios Terry Papoutsakis
May 26, 1999·Proceedings of the National Academy of Sciences of the United States of America·G BeckerR Hengge-Aronis
Jan 22, 2003·Molecular Microbiology·Patrick H ViollierCharles J Thompson
Dec 1, 2004·Genes to Cells : Devoted to Molecular & Cellular Mechanisms·Sousuke ImamuraMakoto Shirai
Nov 6, 2007·Biotechnology and Bioengineering·Akinobu ItoSatoshi Okabe
Feb 13, 2008·Omics : a Journal of Integrative Biology·Radhakrishnan MahadevanJulia Krushkal
Jun 7, 2011·Annual Review of Microbiology·Aurelia BattestiSusan Gottesman
Jan 12, 2013·FEMS Microbiology Letters·Samuel Mohammed ChekababJosée Harel
Jun 27, 2006·Molecular Microbiology·Mirna Mujacic, François Baneyx
Jul 16, 2013·Journal of Bacteriology·Carmen Schwechheimer, Meta J Kuehn
Mar 15, 2005·Critical Reviews in Biochemistry and Molecular Biology·Jeannette Winter, Ursula Jakob
Sep 6, 2001·Biotechnology and Bioengineering·R SrivastavaW E Bentley
Jun 25, 2010·The ISME Journal·Jan Dirk van ElsasJack T Trevors
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Mar 17, 2009·Biotechnology and Bioengineering·Akinobu ItoSatoshi Okabe
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Mar 19, 2008·Applied Microbiology and Biotechnology·Zhen KangQingsheng Qi
Sep 5, 2002·Microbiology and Molecular Biology Reviews : MMBR·Regine Hengge-Aronis
Jun 9, 2006·Microbiology and Molecular Biology Reviews : MMBR·Mee-Jung Han, Sang Yup Lee

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