Heat-shock response in camel (Camelus dromedarius) blood cells and adaptation to hyperthermia

Comparative Biochemistry and Physiology. B, Comparative Biochemistry
H A UlmasovMichael B Evgen'ev

Abstract

1. We demonstrate the difference between the reactions of camel (Camelus dromedarius) lymphocytes and erythrocytes to heat-shock treatment. 2. Lymphocytes of this organism characteristically have a higher resistance of general protein synthesis to elevated temperature in comparison with human lymphocytes. 3. Camel lymphocytes exhibited strong induction of constitutively expressed 73 kDa heat-shock protein (hsp 73) after heat-shock but failed to synthesize an inducible member of the same family (hsp 72) at high temperatures. 4. Nucleated camel erythrocytes do not synthesize any heat-shock proteins after temperature elevation. 5. Western blot analysis, using polyclonal antibody for hsp 73, revealed high levels of this protein in camel lymphocytes and diminished, but significant, amounts of hsp 73 protein in the erythrocytes under normal physiological conditions. 6. The role of 73 kDa hsp in providing thermotolerance of camel blood cells is discussed.

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Citations

May 31, 2007·Journal of Biosciences·Jesper G Sørensen, Volker Loeschcke
May 31, 2007·Journal of Biosciences·M B Evgen'evO G Zatsepina
Dec 3, 2009·Cell Stress & Chaperones·Tal MizrahiZeev Arad
Dec 20, 1994·Proceedings of the National Academy of Sciences of the United States of America·V N LyashkoM B Evgen'ev
Aug 5, 2009·Doklady Biological Sciences : Proceedings of the Academy of Sciences of the USSR, Biological Sciences Sections·M M YurinskayaM B Evgen'ev
Apr 2, 2009·Molekuliarnaia biologiia·D G GarbuzO G Zatsepina
May 27, 2011·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Matthew KuennenPope Moseley
Feb 24, 2015·PloS One·Lyubov N AstakhovaDavid G Garbuz
Feb 2, 2018·International Journal of Molecular Sciences·Abdullah HoterHassan Y Naim
Jun 12, 2010·Annals of the New York Academy of Sciences·Elena RozhkovaMaxim Vinokurov
Jul 6, 2019·Frontiers in Genetics·Abdullah HoterHassan Y Naim
Mar 7, 2019·Frontiers in Genetics·Amanat AliRanjit Vijayan
Feb 12, 2021·Frontiers in Immunology·Jamal Hussen, Hans-Joachim Schuberth

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