Heating potential of iron oxides for therapeutic purposes in interventional radiology

Academic Radiology
I HilgerW A Kaiser

Abstract

In addition to their diagnostic applications, iron oxides could be used therapeutically to eliminate tumors with heat if their heating powers are adequate. The authors therefore examined the specific absorption rate (SAR) of different iron oxide (magnetite) samples suspended in water and in liquid or solidified gel. The authors compared two ferromagnetic fine powders (total particle size, >350 nm and 100 nm), five superparamagnetic ferrofluidic samples (total particle size, 10-280 nm), and a commercially available contrast medium (ferumoxides injectable solution, Endorem). The SARs of the magnetic material-suspended in distilled water or in liquid or solid agar-were estimated from time-dependent calorimetric measurements during exposure to an alternating current magnetic field (amplitude, 6.5 kA/m; frequency, 400 kHz). SARs varied considerably between the different iron oxide samples. The highest value was found for a ferrofluidic sample (>93 W/g), while Endorem had little heating power (<0.1 W/g). The SAR was clearly dependent on the aggregation state of the matrix only for the large-particle-size ferromagnetic sample, yielding the highest values for particle suspensions in water (74 W/g) and lowest for solid agar (8 W/g). The...Continue Reading

References

Apr 1, 1989·AJR. American Journal of Roentgenology·G MarchalE van der Schueren
May 9, 2000·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·D NanzJ F Debatin
Aug 6, 2000·European Journal of Radiology·M F BellinS Precetti-Morel
Oct 1, 1957·Annals of Surgery·R K GILCHRISTC B TAYLOR

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Citations

Aug 7, 2009·Annals of Biomedical Engineering·Chun-Ping JenCheng-Han Tsai
May 8, 2004·Biomaterials·Catherine Cecilia BerryAdam S G Curtis
Oct 8, 2011·International Journal of Nanomedicine·Eva K SchlachterMichael Reinert
Jan 14, 2016·International Journal of Hyperthermia : the Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group·Alexander LeBrunLiang Zhu
Feb 5, 2013·Pharmacological Research : the Official Journal of the Italian Pharmacological Society·Jian-Min ShenFeng Yue
Dec 20, 2011·Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy·D GopiL Kavitha
Feb 11, 2010·Biomaterials·Fahima DilnawazSanjeeb K Sahoo
Jan 8, 2009·Journal of Biomedical Materials Research. Part a·O V MelnikovB M Odintsov
Feb 13, 2013·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Ragy R T RaghebTarek M Fahmy
Sep 5, 2013·International Journal of Hyperthermia : the Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group·Irene Andreu, Eva Natividad
Sep 6, 2012·Expert Opinion on Drug Discovery·Laura Ciani, Sandra Ristori
Oct 11, 2017·Advanced Healthcare Materials·Jalal MosayebiSophie Laurent
Oct 9, 2007·Journal of Biomedical Materials Research. Part B, Applied Biomaterials·N K PrasadD Bahadur
Jan 25, 2005·Philosophical Transactions. Series A, Mathematical, Physical, and Engineering Sciences·Martin KarplusWei Yang
Nov 10, 2013·Journal of Physics. Condensed Matter : an Institute of Physics Journal·A BaezaM Vallet-Regí
Jan 26, 2021·International Journal of Hyperthermia : the Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group·Shuai-Wen DingWei Zhang
Oct 24, 2007·The Journal of Physical Chemistry. B·Prajnaparamita DharThomas M Fischer
Aug 13, 2011·Bioconjugate Chemistry·Sneha S Kelkar, Theresa M Reineke
Dec 10, 2013·Analytical Chemistry·Niall CrawleyAlexander Romaschin
Jul 3, 2013·ACS Applied Materials & Interfaces·Jian-Min ShenShuang Xu

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