PMID: 9534669Apr 16, 1998Paper

Heavy caffeine intake in pregnancy and sudden infant death syndrome. New Zealand Cot Death Study Group

Archives of Disease in Childhood
R P FordA W Stewart

Abstract

To examine the association between maternal caffeine consumption during pregnancy and the risk of sudden infant death syndrome (SIDS). A nationwide case-control study surveying parents of 393 SIDS victims and parents of 1592 control infants. Caffeine consumption in each of the first and third trimesters was estimated by questionnaire. Heavy caffeine intake was defined as 400 mg/day or more (equivalent to four or more cups of coffee per day). Infants whose mothers had heavy caffeine consumption throughout their pregnancy had a significantly increased risk for SIDS (odds ratio 1.65; 95% confidence interval 1.15 to 2.35) after adjusting for likely confounding factors. Caffeine intake has been associated with fetal harm and now SIDS. Reducing heavy caffeine intake during pregnancy could be another way to lessen the risk of SIDS. This needs confirmation by others.

References

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Citations

Nov 18, 2008·Psychopharmacology·Merideth A AddicottPaul J Laurienti
Sep 3, 2002·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·F X Castellanos, J L Rapoport
Jan 10, 2003·Food Additives and Contaminants·P NawrotM Feeley
Jun 1, 2012·Journal of Caffeine Research·Inmaculada Ballesteros-YáñezMairena Martín
Jan 11, 2013·ISRN Cardiology·Ronald Wilders
Jun 1, 2001·Paediatric and Perinatal Epidemiology·F M Sullivan, S M Barlow
Mar 15, 2008·Journal of Human Nutrition and Dietetics : the Official Journal of the British Dietetic Association·E Derbyshire, S Abdula
Apr 15, 1999·Current Opinion in Pediatrics·S D BlattH L Weinberger
Jun 11, 2015·The Cochrane Database of Systematic Reviews·Shayesteh Jahanfar, Sharifah Halimah Jaafar
Jul 18, 2017·Journal of Environmental and Public Health·Declan T WaughWilliam Potter
Jun 4, 2021·Clinical Toxicology : the Official Journal of the American Academy of Clinical Toxicology and European Association of Poisons Centres and Clinical Toxicologists·Isabelle ClaudetUNKNOWN OMIN Study Group

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