Heavy Metals Induce Iron Deficiency Responses at Different Hierarchic and Regulatory Levels

Plant Physiology
Alexandra LeškováNicolaus von Wirén

Abstract

In plants, the excess of several heavy metals mimics iron (Fe) deficiency-induced chlorosis, indicating a disturbance in Fe homeostasis. To examine the level at which heavy metals interfere with Fe deficiency responses, we carried out an in-depth characterization of Fe-related physiological, regulatory, and morphological responses in Arabidopsis (Arabidopsis thaliana) exposed to heavy metals. Enhanced zinc (Zn) uptake closely mimicked Fe deficiency by leading to low chlorophyll but high ferric-chelate reductase activity and coumarin release. These responses were not caused by Zn-inhibited Fe uptake via IRON-REGULATED TRANSPORTER (IRT1). Instead, Zn simulated the transcriptional response of typical Fe-regulated genes, indicating that Zn affects Fe homeostasis at the level of Fe sensing. Excess supplies of cobalt and nickel altered root traits in a different way from Fe deficiency, inducing only transient Fe deficiency responses, which were characterized by a lack of induction of the ethylene pathway. Cadmium showed a rather inconsistent influence on Fe deficiency responses at multiple levels. By contrast, manganese evoked weak Fe deficiency responses in wild-type plants but strongly exacerbated chlorosis in irt1 plants, indicati...Continue Reading

Citations

Apr 19, 2018·Journal of Integrative Plant Biology·Xiani YaoGang Liang
Dec 11, 2019·Environmental Science and Pollution Research International·Lingling FanYi Han
Oct 8, 2019·Journal of Environmental Science and Health. Part. B, Pesticides, Food Contaminants, and Agricultural Wastes·Miroslava PozgajovaAnna Trakovicka
Jan 21, 2020·Journal of Experimental Botany·Sascha WaidmannJürgen Kleine-Vehn
May 13, 2020·International Journal of Phytoremediation·Siamak Shirani Bidabadi
May 21, 2020·Metallomics : Integrated Biometal Science·Massimiliano Corso, Vanesa S García de la Torre
Jun 13, 2020·Plant, Cell & Environment·Benjamin StichNicolaus von Wirén
Apr 11, 2020·Frontiers in Plant Science·Santiago AlejandroEdgar Peiter
Dec 19, 2018·Environmental Science and Pollution Research International·Jyoti Ranjan RoutMathummal Sudarshan
May 7, 2020·Frontiers in Plant Science·Monirul IslamGianpiero Vigani
Feb 16, 2018·Journal of Experimental Botany·Elisa AndresenHendrik Küpper
Apr 17, 2020·International Journal of Molecular Sciences·Ali Anwar, Ju-Kon Kim
Nov 12, 2020·Journal of Experimental Botany·Marc HanikenneHatem Rouached
Aug 4, 2019·Ecotoxicology and Environmental Safety·Nisha ShabnamHyunook Kim
Nov 29, 2020·Trends in Plant Science·Kevin RobeChristian Dubos
May 28, 2021·Planta·Harmanjit Kaur, Neera Garg
May 28, 2021·Frontiers in Plant Science·Suresh KumarTrilochan Mohapatra
Aug 27, 2021·Toxics·Ruchi BansalKadambot H M Siddique
Sep 10, 2021·Journal of Experimental Botany·Samuel A McInturfDavid G Mendoza-Cózatl
Oct 9, 2021·Plant, Cell & Environment·Dorina Podar, Frans J M Maathuis
Oct 12, 2021·Chemosphere·Paulo Ademar Avelar FerreiraLuiz Roberto Guimarães Guilherme
Dec 25, 2021·Molecular Plant·Camilla StantonDorina Podar
Dec 18, 2021·Molecular Plant·Zhongtao JiaNicolaus von Wirén

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