PMID: 6538687Mar 1, 1984Paper

Heightened aggressive behavior by animals interacting with alcohol-treated conspecifics: studies with mice, rats and squirrel monkeys

Pharmacology, Biochemistry, and Behavior
K A MiczekJ F DeBold

Abstract

Drug-free mice, rats and squirrel monkeys showed more aggression toward alcohol-treated conspecifics than under control conditions. Quantitative ethological analysis was used to assess the dose-dependent effects of ethyl alcohol on a range of aggressive, submissive, defensive, escape responses as well as on non-agonistic behavior such as associative responses, grooming, and locomotor activities. Two experimental situations were studied: resident-intruder confrontations in mice and rats, and interactions between members of established groups of squirrel monkeys. After PO administration of ethyl alcohol to intruder mice and rats, the non-drugged resident mice and rats attacked, threatened, and pursued intruders at higher frequencies during 5-min encounters. Similarly, subordinate squirrel monkeys who were members of three established groups, when given alcohol, were grasped, displaced, and displayed to more frequently by non-drugged group members than after water control injections during the first 40 min after injection. This change in aggressive behavior by non-drugged animals was related to the alcohol dose given to the intruder or subordinate animal; near-ataxic alcohol doses (3.0 g/kg in mice, 1.7 g/kg in rats, 1.0 g/kg in s...Continue Reading

References

Feb 28, 1979·Psychopharmacology·T F Pettijohn
May 9, 1977·Psychopharmacology·K A Miczek, H Barry
Dec 21, 1976·Psychopharmacology·M Krsiak
Jan 1, 1974·Behaviour·J Altmann
Jan 1, 1973·Psychopharmacologia·M Krsiak, M Borgesová
Dec 1, 1973·Journal of Comparative and Physiological Psychology·R B Cairns, S D Scholz
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Jan 1, 1980·Psychopharmacology·K A Miczek, J M O'Donnell
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Jan 1, 1981·Pharmacology, Biochemistry, and Behavior·J F DeBold, K A Miczek
Mar 19, 1982·Science·K A MiczekL Shuster

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Citations

Jan 1, 1985·Psychopharmacology·J F DeBold, K A Miczek
Sep 1, 1995·Psychopharmacology·K A MiczekH M Barros
Aug 17, 2012·Psychopharmacology·Michael A NaderDrake Morgan
Jan 1, 1986·Physiology & Behavior·R J BlanchardK Hori
Mar 1, 1986·Pharmacology, Biochemistry, and Behavior·T F KalhornJ T Slattery
Jan 1, 1987·Pharmacology, Biochemistry, and Behavior·R J BlanchardD C Blanchard
Jan 1, 1990·Pharmacology & Therapeutics·S V Vellucci
May 17, 2005·Pharmacology, Biochemistry, and Behavior·Robert D Hienz, Elise M Weerts
Dec 4, 2003·Pharmacology & Therapeutics·Kathleen A Grant, Allyson J Bennett
Sep 20, 1996·Annals of the New York Academy of Sciences·C F Ferris, J Brewer
Apr 22, 2009·Behavioural Brain Research·Michel Pratte, Marc Jamon
Aug 19, 2015·Annals of the New York Academy of Sciences·Klaus A MiczekRosa M M de Almeida

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