Helical sense selective domains and enantiomeric superhelices generated by Langmuir-Schaefer deposition of an axially racemic chiral helical polymer

Nanoscale
R RodríguezFélix Freire

Abstract

The chiral polymer poly-(R)-1 behaves in solution, despite its chiral pendants, as a dynamic axially racemic (i.e., 1 : 1) mixture of left- and right-handed helices, but its deposition on graphite by a Langmuir-Schaefer (LS) technique leads to a helical sense-selective packing that forms separate enantiomeric domains of left- and right-handed helical chains observed by high resolution atomic force microscopy (AFM). The polymer structure within these domains is very uniform, seldom altered by the presence of reversals, grouped always in contiguous pairs maintaining a single helical sense along the polymer chain. The LS deposition technique has been shown to be crucial to obtain good quality monolayers from poly-(R)-1 and other poly(phenylacetylene)s (PPAs: poly-2, poly-3 and poly-4) with short pendants, where spin coating, drop casting and Langmuir-Blodgett (LB) failed, and suggests that this technique could be the method of choice for the preparation of 2D monolayers for high resolution AFM studies of PPAs with short pendants. Key helical parameters (i.e., sense, pitch, packing angle) are easily measured in this way.

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Citations

Jul 16, 2016·Journal of the American Chemical Society·Rafael RodríguezFélix Freire
Jul 18, 2017·Chemical Communications : Chem Comm·Mohammad AlzubiFélix Freire
Jul 3, 2021·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Berta FernándezFélix Freire
Dec 15, 2017·Journal of the American Chemical Society·Sandra AriasFélix Freire
Jul 20, 2018·Journal of the American Chemical Society·Jake L GreenfieldJonathan R Nitschke
Aug 30, 2018·Journal of the American Chemical Society·Katherine CobosFélix Freire

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