Helicobacter pylori and hepatocellular carcinoma: correlated or uncorrelated?

Journal of Gastroenterology and Hepatology
Xiong Zhi Wu, Dan Chen

Abstract

Helicobacter pylori can be detected in liver tissue resected from patients with hepatocellular carcinoma. Conflicting reports regarding the relationship between H. pylori and hepatocellular carcinoma mean it is uncertain whether H. pylori acts as a troublemaker, co-risk factor or innocent bystander to the development of hepatocellular carcinoma. Clinical studies in patients without known causes of hepatocellular carcinoma are important to discover whether H. pylori is involved in the carcinogenesis of hepatocellular carcinoma. High quality prospective studies in patients with hepatocellular carcinoma, hepatitis C virus infection and no cirrhosis are needed to determine whether H. pylori is a co-risk factor for hepatocellular carcinoma.

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Citations

Jul 11, 2006·Journal of Gastroenterology and Hepatology·Xiong-Zhi Wu, Dan Chen
Jan 12, 2008·World Journal of Gastroenterology : WJG·Shi-Ying XuanHua-Shi Guan
Oct 24, 2007·Human Pathology·Perumal Vivekanandan, Michael Torbenson
Feb 16, 2007·Medical Hypotheses·Xiong-Zhi Wu, Xiao-Hui Yu
Aug 24, 2006·Helicobacter·Teresa Starzyñska, Peter Malfertheiner
Oct 17, 2014·World Journal of Gastroenterology : WJG·Xing-Nan PanXiao-Huan Lai

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