PMID: 9174219Apr 1, 1997Paper

Helicobacter pylori duodenal colonization in children

Acta Paediatrica
M BonamicoF Carpino

Abstract

To investigate the prevalence and the significance of Helicobacter pylori duodenal colonization, endoscopic duodenal biopsies were performed in 168 children with chronic abdominal pain, gastroesophageal reflux, gastrointestinal bleeding, and malabsorption syndrome. Helicobacter pylori infection was detected in 68 children (40.4%): in 31 of them H. pylori was present in the gastric antrum, and in 37 in the duodenum also. Duodenitis was observed in 25 children with duodenal H. pylori; gastric metaplasia in 3. Scanning electron microscopy revealed the presence of the micro-organism in 3/13 cases; the bacteria were located in the intercellular spaces and alterations of the epithelial surface were found. In conclusion, H. pylori gastritis in children is often associated with duodenal colonization which can cause duodenitis, and also without gastric metaplasia, which indicates a possible role of the micro-organism in the pathogenesis of the lesions.

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Citations

Oct 9, 2002·Cellular Microbiology·Manuel R AmievaStanley Falkow
Apr 5, 2000·Journal of Pediatric Gastroenterology and Nutrition·K L Kolho, E Savilahti
Jun 30, 2009·Archives of Orthopaedic and Trauma Surgery·Martin EllenriederWolfram Mittelmeier
Feb 20, 2007·Alimentary Pharmacology & Therapeutics·R KhuranaB D Gold
Apr 14, 2017·The Journal of Venomous Animals and Toxins Including Tropical Diseases·Marina SaesSpencer Luiz Marques Payão

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